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PSMB10 wt Allele

Known as: LMP10, beta2i, MGC1665 
Human PSMB10 wild-type allele is located in the vicinity of 16q22.1 and is approximately 3 kb in length. This allele, which encodes proteasome… 
National Institutes of Health

Related topics

Related topics

7 relations
16q22.1Antigen ProcessingHydrolysisProteasome Pathway

Papers overview

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2016
2016
Proteasome β5i Subunit Deficiency Affects Opsonin Synthesis and Aggravates Pneumococcal Pneumonia
Immunoproteasomes, harboring the active site subunits β5i/LMP7, β1i/LMP2, and β2i/MECL1 exert protective, regulatory or… 
2009
2009
Differential expression of constitutive and inducible proteasome subunits in human monocyte‐derived DC differentiated in the presence of IFN‐α or IL‐4
Several studies strongly suggest that DC differentiated in vitro in the presence of type I IFN acquire more potent immune… 
2008
2008
Autoimmune reactivity against the 20S-proteasome includes immunosubunits LMP2 (beta1i), MECL1 (beta2i) and LMP7 (beta5i).
OBJECTIVES Autoantibodies against the 20S-proteasome display a broad diversity with a remarkably low frequency of individual… 
Highly Cited
2003
Highly Cited
2003
Genes of the LMP/TAP cluster are associated with the human autoimmune disease vitiligo
Genes within the class II region of the major histocompatibility complex (MHC), including genes involved in antigen processing… 
Highly Cited
2001
Highly Cited
2001
Bipartite regulation of different components of the MHC class I antigen-processing machinery during dendritic cell maturation.
Dendritic cells (DC) are professional antigen-presenting cells (APC) which proceed from immature to a mature stage during their… 
2001
2001
Prognostic significance of immuno-proteosome subunit expression in patients with renal-cell carcinoma: a preliminary study.
Our purpose was to elucidate the clinical roles of the "immuno-proteosome," which is involved in the accelerated pathway of the… 
1999
1999
Interferon Regulatory Factor 1 Mediates the Interferon-γ Induction of the Human Immunoproteasome Subunit Multicatalytic Endopeptidase Complex-like 1*
Proteasomes generate antigenic peptides from intracellular proteins for presentation to the immune system by the major… 
1998
1998
Constitutive and interferon-gamma-induced expression of the human proteasome subunit multicatalytic endopeptidase complex-like 1.
1997
1997
The mouse genes encoding the third pair of beta-type proteasome subunits regulated reciprocally by IFN-gamma: structural comparison, chromosomal localization, and analysis of the promoter.
Proteasomes are the multisubunit protease involved in the generation of peptides presented by MHC class I molecules. When cells… 
1997
1997
DNA sequence, chromosomal localization, and tissue expression of the mouse proteasome subunit lmp10 (Psmb10) gene.
Proteasomes are nonlysosomal multicatalytic proteases involved in antigen processing. Three of the 10 mammalian proteasome beta… 
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