16q22.1

A chromosome band present on 16q
National Institutes of Health

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19 relations
16qACD wt AlleleCDH1 wt AlleleCDH3 wt Allele
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Papers overview

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Highly Cited
2012
Highly Cited
2012
Characterization of gene-environment interactions for colorectal cancer susceptibility loci.
Genome-wide association studies (GWAS) have identified more than a dozen loci associated with colorectal cancer (CRC) risk. Here… (More)
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Highly Cited
2009
Highly Cited
2009
CMTM3, located at the critical tumor suppressor locus 16q22.1, is silenced by CpG methylation in carcinomas and inhibits tumor cell growth through inducing apoptosis.
Closely located at the tumor suppressor locus 16q22.1, CKLF-like MARVEL transmembrane domain-containing member 3 and 4 (CMTM3 and… (More)
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Highly Cited
2009
Highly Cited
2009
Spinocerebellar ataxia type 31 is associated with "inserted" penta-nucleotide repeats containing (TGGAA)n.
Spinocerebellar ataxia type 31 (SCA31) is an adult-onset autosomal-dominant neurodegenerative disorder showing progressive… (More)
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Highly Cited
2008
Highly Cited
2008
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer
Genome-wide association (GWA) studies have identified multiple loci at which common variants modestly influence the risk of… (More)
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2007
2007
Redefining the disease locus of 16q22.1-linked autosomal dominant cerebellar ataxia
AbstractThe 16q22.1-linked autosomal dominant cerebellar ataxia (16q-ADCA; Online Mendelian Inheritance in Man [OMIN] #117210) is… (More)
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2005
2005
An autosomal dominant cerebellar ataxia linked to chromosome 16q22.1 is associated with a single-nucleotide substitution in the 5' untranslated region of the gene encoding a protein with spectrin…
Autosomal dominant cerebellar ataxia (ADCA) is a group of heterogeneous neurodegenerative disorders. By positional cloning, we… (More)
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Review
2001
Review
2001
The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression
E-cadherin is a cell–cell adhesion protein fulfilling a prominent role in epithelial differentiation. Data from model systems… (More)
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Highly Cited
2001
Highly Cited
2001
Mechanisms of inactivation of E-cadherin in breast carcinoma: modification of the two-hit hypothesis of tumor suppressor gene
Loss of heterozygosity (LOH) allows the expression of recessive mutation in tumor suppressor genes (TSG). Therefore, on the basis… (More)
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Highly Cited
1996
Highly Cited
1996
Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family.
We report the cloning, sequence analysis, tissue distribution, and functional expression of the K-Cl cotransport protein, KCC1… (More)
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Highly Cited
1990
Highly Cited
1990
Allele loss on chromosome 16 associated with progression of human hepatocellular carcinoma.
Loss of heterozygosity on chromosome 16 is a common genetic alteration in human hepatocellular carcinoma (HCC). To clarify the… (More)
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