16q22.1

Genome-wide association (GWA) studies have identified multiple loci at which common variants modestly influence the risk of… Expand

E-cadherin is a cell–cell adhesion protein fulfilling a prominent role in epithelial differentiation. Data from model systems… Expand

Loss of heterozygosity (LOH) allows the expression of recessive mutation in tumor suppressor genes (TSG). Therefore, on the basis… Expand

The cellular protooncogene MYC encodes a nuclear transcription factor that is involved in regulating important cellular functions… Expand

Our study was designed to clarify the significance of silencing the E‐cadherin gene, which is located on 16q22.1, due to CpG… Expand

The hereditary ataxias represent a clinically and genetically heterogeneous group of neurodegenerative disorders. Various… Expand

We have analysed a series of 49 human breast cancers for mutations in the entire coding region plus flanking intron sequences of… Expand

We report the cloning, sequence analysis, tissue distribution, and functional expression of the K-Cl cotransport protein, KCC1… Expand

Compelling experimental evidence exists for a potent invasion suppressor role of the cell‐cell adhesion molecule E‐cadherin. In… Expand

A human genomic clone for a novel fifth member of the Na+/H+ exchanger (NHE) family, NHE5 (gene symbol SLC9A5), has been isolated… Expand