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PRKD2 gene

Known as: PRKD2, Protein Kinase D2 Gene, HSPC187 
This gene is involved in the protein kinase C signaling cascade.
National Institutes of Health

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PRKD2 wt Allele
PhosphorylationSerine/Threonine PhosphorylationSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The Role and Mechanism of CRT 0066101 as an Effective Drug for Treatment of Triple-Negative Breast Cancer
Background/Aims: Breast cancer is clinically classified into three main subtypes: estrogen receptor-positive (ER+) breast cancer… 
2018
2018
1 Identification of Novel Mutational Drivers Reveals Oncogene Dependencies In Multiple Myeloma . Short title : Oncogene dependencies in myeloma
Understanding the profile of oncogene and tumor suppressor gene mutations with their interactions and impact on the prognosis of… 
2017
2017
Frequent low‐level mutations of protein kinase D2 in angiolipoma
Tumours displaying differentiation towards normal fat constitute the most common subgroup of soft tissue neoplasms. A series of… 
2017
2017
Identification of Novel Oncogenes and Tumor Suppressor Genes in Newly Diagnosed Multiple Myeloma
Introduction. Identifying driver genes in multiple myeloma (MM) will have a number of key benefits as they can directly affect… 
2013
2013
PRKD2 Serine-Threonine Kinase, a Downstream Effector Of GABP, Plays Essential Roles For The Maintenance Of HSCs
Hematopoietic stem cells (HSCs) are the source of all blood lineages, and HSCs must balance quiescence, self-renewal, and… 
2013
2013
Protein kinase D2 and heat shock protein 90 beta are required for BCL6-associated zinc finger protein mRNA stabilization induced by vascular endothelial growth factor-A
Vascular endothelial growth factor (VEGF) is a major angiogenic factor that activates pro-angiogenic molecules to generate new… 
2012
2012
PRKD2 Serine-Threonine Kinase, an Essential Effector of Gabp Transcription Factor, Is Required for Development of Chronic Myelogenous Leukemia
Abstract 1672 Chronic Myelogenous Leukemia (CML) is a myeloproliferative neoplasm (MPN) caused by transformation of hematopoietic… 
2009
2009
Abstract #96: Confirmation of a set of genetic susceptibility variants for chronic lymphocytic leukemia (CLL)
Background: CLL is the most common adult leukemia in the United States, and there is strong and consistent evidence that a… 
2008
2008
NCAM as a cystogenesis marker gene of PKD2 overexpression.
ADPKD (Autosomal Dominant Polycystic Kidney Disease) is characterized by the progressive expansion of multiple cystic lesions in… 
2006
2006
Overexpression of wild-type PKD2 leads to increased proliferation and invasion of BON endocrine cells.
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