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PPP1R15A wt Allele

Known as: GADD34, Growth Arrest and DNA-Damage-Inducible 34 Gene, Growth Arrest and DNA-Damage-Inducible Gene 34 
Human PPP1R15A wild-type allele is located in the vicinity of 19q13.2 and is approximately 4 kb in length. This allele, which encodes protein… 
National Institutes of Health

Related topics

Related topics

7 relations
19q13.2BMP Receptor Signaling PathwayCellular Stress ResponseNegative Regulation of Cell Cycle

Broader (1)

PPP1R15A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Pharmacokinetics explain in vivo/in vitro discrepancies of carcinogen-induced gene expression alterations in rat liver and cultivated hepatocytes
Cultivated hepatocytes represent a well-established in vitro system. However, the applicability of hepatocytes in toxicogenomics… 
Highly Cited
2008
Highly Cited
2008
Control of Cellular GADD34 Levels by the 26S Proteasome
ABSTRACT GADD34, the product of a growth arrest and DNA damage-inducible gene, is expressed at low levels in unstressed cells. In… 
2008
2008
A Point Mutation in Translation Initiation Factor 2B Leads to a Continuous Hyper Stress State in Oligodendroglial-Derived Cells
Background Mutations in eukaryotic translation initiation factor 2B (eIF2B) cause Childhood Ataxia with CNS Hypomyelination (CACH… 
2007
2007
Regulatory proteins of eukaryotic initiation factor 2‐alpha subunit (eIF2α) phosphatase, under ischemic reperfusion and tolerance
Phosphorylation of the α subunit of eukaryotic translation initiation factor 2 (eIF2α), which is one of the substrates of protein… 
2006
2006
Radiation-Induced Cellular DNA Damage Repair Response Enhances Viral Gene Therapy Efficacy in the Treatment of Malignant Pleural Mesothelioma
BackgroundMalignant pleural mesothelioma (MPM) treated with radiotherapy (RT) has incomplete responses as a result of radiation… 
2005
2005
Potential molecular mechanism for rodent tumorigenesis: mutational generation of Progression Elevated Gene-3 (PEG-3)
Progression Elevated Gene-3 (PEG-3) was cloned using subtraction hybridization as an upregulated transcript associated with… 
Highly Cited
2004
Highly Cited
2004
Endoplasmic reticulum stress as a correlate of cytotoxicity in human tumor cells exposed to diindolylmethane in vitro
Abstract The dietary phytochemical indole-3-carbinol (I3C) protects against cervical cancer in animal model studies and in human… 
2004
2004
GADD34 protein levels increase after transient ischemia in the cortex but not in the CA1 subfield: implications for post‐ischemic recovery of protein synthesis in ischemia‐resistant cells
Transient cerebral ischemia is a pathological process whereby an irreversible suppression of protein synthesis is believed to… 
Highly Cited
2003
Highly Cited
2003
Ischaemic preconditioning in the rat brain: effect on the activity of several initiation factors, Akt and extracellular signal‐regulated protein kinase phosphorylation, and GRP78 and GADD34…
Translational repression induced during reperfusion of the ischaemic brain is significantly attenuated by ischaemic… 
1999
1999
Evidence for the interaction between Translin and GADD34 in mammalian cells.
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