PPP1R15A wt Allele

Known as: GADD34, Growth Arrest and DNA-Damage-Inducible 34 Gene, Growth Arrest and DNA-Damage-Inducible Gene 34 
Human PPP1R15A wild-type allele is located in the vicinity of 19q13.2 and is approximately 4 kb in length. This allele, which encodes protein… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The mechanisms leading to neuronal death in neurodegenerative disease are poorly understood. Many of these disorders, including… (More)
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Highly Cited
2008
Highly Cited
2008
Protein misfolding, accumulation, and aggregation characterize many aging-related diseases. Protein aggregates do not accumulate… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Gliomas treated with the alkylating agent temozolomide have incomplete responses in part because of tumoral repair of… (More)
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Highly Cited
2004
Highly Cited
2004
Hypoxic stress results in a rapid and sustained inhibition of protein synthesis that is at least partially mediated by eukaryotic… (More)
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Highly Cited
2003
Highly Cited
2003
The growth arrest and DNA damage-inducible protein, GADD34, associates with protein phosphatase 1 (PP1) and promotes in vitro… (More)
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Highly Cited
2003
Highly Cited
2003
Phosphorylation of eukaryotic translation initiation factor 2alpha (eIF2alpha) on serine 51 is effected by specific stress… (More)
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Highly Cited
2003
Highly Cited
2003
GADD34 is a protein that is induced by stresses such as DNA damage. The function of mammalian GADD34 has been proposed by in… (More)
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Highly Cited
2001
Highly Cited
2001
The growth arrest and DNA damage-inducible protein, GADD34, was identified by its interaction with human inhibitor 1 (I-1), a… (More)
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Highly Cited
2001
Highly Cited
2001
Phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha) on serine 51 integrates general… (More)
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Highly Cited
1997
Highly Cited
1997
The mammalian cellular response to genotoxic stress is a complex process involving many known and probably many as yet unknown… (More)
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