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PPP1R15A gene

Known as: growth arrest and DNA-damage-inducible 34, GADD34, Protein Phosphatase 1, Regulatory Subunit 15A Gene 
This gene is involved in phosphatase regulation.
National Institutes of Health

Papers overview

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2017
2017
Dephosphorylation of translation initiation factor 2 (eIF2α) terminates signalling in the mammalian integrated stress response… Expand
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2017
2017
The reversible phosphorylation of proteins controls most cellular functions. Protein kinases have been popular drug targets… Expand
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Highly Cited
2015
Highly Cited
2015
Giving protein folding a helping hand The reversible phosphorylation of proteins controls virtually all aspects of cell and… Expand
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Highly Cited
2014
Highly Cited
2014
BackgroundOvarian cancer (OCa) peritoneal metastasis is the leading cause of cancer–related deaths in women with limited… Expand
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Highly Cited
2011
Highly Cited
2011
Guanabenz, a small-molecule inhibitor, protects cells from lethal accrual of misfolded proteins in the endoplasmic reticulum… Expand
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Highly Cited
2011
Highly Cited
2011
Background The endoplasmic reticulum (ER) is the cellular site for protein folding. ER stress occurs when protein folding… Expand
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Highly Cited
2009
Highly Cited
2009
Cellular stress such as endoplasmic reticulum stress, hypoxia, and viral infection activates an integrated stress response, which… Expand
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2008
2008
Galectin (Gal) 1 is a hypoxia-regulated proangiogenic factor that also directly participates in glioblastoma cell migration. To… Expand
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2008
2008
GADD34, the product of a growth arrest and DNA damage-inducible gene, is expressed at low levels in unstressed cells. In response… Expand
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Highly Cited
2008
Highly Cited
2008
IntroductionAbout 30% of rheumatoid arthritis patients fail to respond adequately to TNFα-blocking therapy. There is a medical… Expand
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