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PPP1R15A gene

Known as: growth arrest and DNA-damage-inducible 34, GADD34, Protein Phosphatase 1, Regulatory Subunit 15A Gene 
This gene is involved in phosphatase regulation.
National Institutes of Health

Related topics

Related topics

4 relations
Cellular Stress ResponseNegative Regulation of Cell CycleTranslational Activation

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PPP1R15A wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The antibiotic robenidine exhibits guanabenz-like cytoprotective properties by a mechanism independent of protein phosphatase PP1:PPP1R15A
The aminoguanidine compound robenidine is widely used as an antibiotic for the control of coccidiosis, a protozoal infection in… 
2016
2016
Feasibility of novel PPP1R15A and proposed ANXA11 single nucleotide polymorphisms as predictive markers for bevacizumab regimen in metastatic colorectal cancer
PurposeBevacizumab improves survival in patients with metastatic colorectal cancer (mCRC) under chemotherapy, but few predictive… 
2016
2016
Effect of diesel exhaust (DE) on stress responses and innate immunity in primary bronchial epithelial cell (PBEC) cultures from patients with COPD and controls
Exposure to diesel emissions is associated with adverse effects on respiratory health, especially in COPD and asthma. We… 
2016
2016
Murine model of obesity-induced type II diabetes by GADD34 (PPP1R15A) and other phosphatase 1 regulatory subunits deficiency.
Obesity-derived metabolic syndrome is one of the most important medical problems in the world. Recently, we have developed murine… 
2016
2016
Commentary: A novel infection- and inflammation-associated molecular signature in peripheral blood of myasthenia gravis patients
Early-onset acetylcholine receptor-positive myasthenia gravis is the most studied and better-characterized clinical subgroup of… 
2015
2015
Anemone altaica Induces Apoptosis in Human Osteosarcoma Cells.
In the past decade, no significant improvement has been made in chemotherapy for osteosarcoma (OS). To develop improved agents… 
2015
2015
Alteration of DNA damage signaling pathway profile in radiation-treated glioblastoma stem-like cells.
The present study aimed to investigate the alteration of the DNA damage signaling pathway profile in radiation-treated… 
2013
2013
Unraveling toxicological mechanisms and predicting toxicity classes with gene dysregulation networks
The use of genes for distinguishing classes of toxicity has become well established. In this paper we combine the reconstruction… 
Highly Cited
2008
Highly Cited
2008
Control of Cellular GADD34 Levels by the 26S Proteasome
ABSTRACT GADD34, the product of a growth arrest and DNA damage-inducible gene, is expressed at low levels in unstressed cells. In… 
2000
2000
Characterization of a murine gene encoding an acidic‐basic dipeptide repeat that interacts with GADD34
GADD34 is one of a subset of proteins induced after DNA damage or cell growth arrest. To examine the function of GADD34, we used… 
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