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PPP1R13L wt Allele

Known as: NKIP1, Inhibitor of Apoptosis Stimulating Protein of P53 Gene, IASPP 
Human PPP1R13L wild-type allele is located in the vicinity of 19q13.32 and is approximately 27 kb in length. This allele, which encodes RelA… 
National Institutes of Health

Related topics

Related topics

4 relations
19q13.32ApoptosisTranscriptional Repression

Broader (1)

PPP1R13L gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
iASPP overexpression is associated with clinical outcome in spinal chordoma and influences cellular proliferation, invasion, and sensitivity to cisplatin in vitro
The oncogenetic function of inhibitory member of the apoptosis stimulating protein of p53 family (iASPP) in chordoma is unclear… 
2014
2014
Nuclear iASPP may facilitate prostate cancer progression
One of the major challenges in prostate cancer (PCa) research is the identification of key players that control the progression… 
2011
2011
Inhibitory member of the apoptosis-stimulating protein of p53 (ASPP) family promotes growth and tumorigenesis in human p53-deficient prostate cancer cells
iASPP is a member of the apoptosis-stimulating protein of p53 (ASPP) family and an evolutionarily conserved inhibitor of p53… 
2011
2011
Down-regulation of iASPP in human hepatocellular carcinoma cells inhibits cell proliferation and tumor growth.
Abstract The oncoprotein inhibitory member of the ASPP family (iASPP) is a key inhibitor of the p53 tumor suppressor and is… 
2011
2011
iASPP is important for bladder cancer cell proliferation.
Inhibitor of apoptosis stimulatory protein phosphatase (iASPP) is a key inhibitor of p53 conserved from worm to human and is… 
2010
2010
Lentiviral vector-mediated doxycycline-inducible iASPP gene targeted RNA interference in hepatocellular carcinoma.
BACKGROUND AND OBJECTIVE iASPP, an inhibitory member of the apoptosis-stimulating proteins of p53 (ASPP) family, has been found… 
2009
2009
iASPP, a potential drug target in cancer therapy.
Review
2008
Review
2008
iASPP inhibition: increased options in targeting the p53 family for cancer therapy.
Strategies to induce p53 for cancer therapy offer appeal but many tumors harbor inactivating p53 mutations. One way to address… 
2007
2007
Expression of the RAI gene is conducive to apoptosis: studies of induction and interference.
2007
2007
Solution structure of ASPP2 N-terminal domain (N-ASPP2) reveals a ubiquitin-like fold.
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