PPARG gene

Known as: peroxisome proliferator activated receptor gamma, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA, PPARgamma 
This gene plays a regulatory role in adipocyte differentiation.
National Institutes of Health

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Biologic DevelopmentCell Differentiation processCell ProliferationDiabetes Mellitus, Non-Insulin-Dependent
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PPARG wt Allele

Papers overview

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Highly Cited
2014
Highly Cited
2014
β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors.
The transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator-1α (PGC-1α) regulates metabolic… (More)
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Highly Cited
2013
Highly Cited
2013
Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology?
Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are n-3 fatty acids found in oily fish and fish oil supplements. These… (More)
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Highly Cited
2010
Highly Cited
2010
Impact of Common Variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the Risk of Type 2 Diabetes in 5,164 Indians
OBJECTIVE Common variants in PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 genes have been shown to be… (More)
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Highly Cited
2009
Highly Cited
2009
PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 Are Associated with Type 2 Diabetes in a Chinese Population
BACKGROUND Recent advance in genetic studies added the confirmed susceptible loci for type 2 diabetes to eighteen. In this study… (More)
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Highly Cited
2007
Highly Cited
2007
Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma.
Transrepression is widely utilized to negatively regulate gene expression, but the mechanisms by which different nuclear… (More)
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Highly Cited
2003
Highly Cited
2003
Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor-gamma coactivator-1 and peroxisome proliferator-activated receptor-alpha in…
The peroxisome proliferator-activated receptor (PPAR)-gamma coactivator-1 (PGC-1) can induce mitochondria biogenesis and has been… (More)
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Review
2002
Review
2002
Insulin resistance as the core defect in type 2 diabetes mellitus.
Insulin resistance is a major contributor to the pathogenesis of type 2 diabetes and plays a key role in associated metabolic… (More)
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Highly Cited
2002
Highly Cited
2002
A novel heterozygous mutation in peroxisome proliferator-activated receptor-gamma gene in a patient with familial partial lipodystrophy.
Familial partial lipodystrophies (FPL) are a heterogeneous group of genetic disorders characterized by marked loss of… (More)
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Highly Cited
2001
Highly Cited
2001
The peroxisome proliferator-activated receptor delta promotes lipid accumulation in human macrophages.
The peroxisome proliferator-activated receptors (PPARs) are a family of fatty acid-activated transcription factors which control… (More)
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Review
2001
Review
2001
Peroxisome proliferator-activated receptors: from genes to physiology.
The peroxisome proliferator-activated receptors (PPARalpha, gamma, delta) are members of the nuclear receptor superfamily of… (More)
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