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PPARG gene

Known as: peroxisome proliferator activated receptor gamma, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA, PPARgamma 
This gene plays a regulatory role in adipocyte differentiation.
National Institutes of Health

Related topics

Related topics

29 relations
Biologic DevelopmentCell Differentiation processCell ProliferationDiabetes Mellitus, Non-Insulin-Dependent

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PPARG wt Allele

Papers overview

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Highly Cited
2008
Highly Cited
2008
Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARgamma agonist.
Most physiologically induced examples of recruitment of brown adipose tissue (BAT) occur as a consequence of chronic sympathetic… 
Highly Cited
2008
Highly Cited
2008
Insulin-resistant muscle is exercise resistant: evidence for reduced response of nuclear-encoded mitochondrial genes to exercise.
Mitochondrial dysfunction, associated with insulin resistance, is characterized by low expression of peroxisome proliferator… 
Highly Cited
2007
Highly Cited
2007
Oxidant Stress Impairs In Vivo Reendothelialization Capacity of Endothelial Progenitor Cells From Patients With Type 2 Diabetes Mellitus: Restoration by the Peroxisome Proliferator-Activated Receptor…
Background— Endothelial progenitor cells (EPCs) are thought to contribute to endothelial recovery after arterial injury. We… 
Highly Cited
2007
Highly Cited
2007
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone.
CONTEXT The common P12A polymorphism in PPARG (a target for thiazolidinedione medications) has been consistently associated with… 
Highly Cited
2005
Highly Cited
2005
Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction.
Reduced IGF-I/insulin signaling and caloric restriction (CR) are known to extend the life span and delay age-related diseases. To… 
Highly Cited
2003
Highly Cited
2003
The PPAR‐gamma P12A polymorphism modulates the relationship between dietary fat intake and components of the metabolic syndrome: results from the Québec Family Study
The metabolic syndrome is a complex disorder characterized by an atherogenic dyslipidemia resulting from the interaction between… 
Highly Cited
2003
Highly Cited
2003
A licorice ethanolic extract with peroxisome proliferator-activated receptor-gamma ligand-binding activity affects diabetes in KK-Ay mice, abdominal obesity in diet-induced obese C57BL mice and…
The metabolic syndrome, including type 2 diabetes, insulin resistance, obesity/abdominal obesity, hypertension and dyslipidemia… 
Highly Cited
2001
Highly Cited
2001
Differential effects of flavonoids on 3T3-L1 adipogenesis and lipolysis.
Flavonoids, polyphenolic compounds that exist widely in plants, inhibit cell proliferation and increase cell differentiation in… 
Highly Cited
1999
Highly Cited
1999
Troglitazone, an antidiabetic agent, inhibits cholesterol biosynthesis through a mechanism independent of peroxisome proliferator-activated receptor-gamma.
Troglitazone is an antidiabetic agent of the thiazolidinedione family. It is generally believed that thiazolidinediones exert… 
Highly Cited
1998
Highly Cited
1998
Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated…
A radioiodinated ligand, [125I]SB-236636 [(S)-(-)3-[4-[2-[N-(2-benzoxazolyl)-N-methylamino]ethoxy]3-[125I]i odo phenyl]2-ethoxy… 
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