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POU5F1 gene

Known as: OCTAMER-BINDING TRANSCRIPTION FACTOR 4, POU Domain, Class 5, Transcription Factor 1 Gene, POU class 5 homeobox 1 
This gene plays a role in early mammalian development.
National Institutes of Health

Related topics

Related topics

12 relations
Cell Differentiation processEWSR1/POU5F1 Fusion GeneHomo sapiensMorphogenesis

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POU5F1 wt Allele

Papers overview

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Highly Cited
2013
Highly Cited
2013
The stem cell markers Oct4A, Nanog and c-Myc are expressed in ascites cells and tumor tissue of ovarian cancer patients
The aim of this study was to examine the expression of established stem cell markers in ascites and tumor tissue obtained from… 
Highly Cited
2012
Highly Cited
2012
Nanog and Oct4 overexpression increases motility and transmigration of melanoma cells
PurposeMelanoma tumors are highly heterogeneous and can undergo phenotypic modifications depending on their plasticity and the… 
Highly Cited
2011
Highly Cited
2011
Selection of radioresistant tumor cells and presence of ALDH1 activity in vitro.
2011
2011
CD133, OCT4, and NANOG in ulcerative colitis-associated colorectal cancer.
Stem cells are thought to contribute to tissue regeneration as well as carcinogenesis. Ulcerative colitis-associated colorectal… 
2011
2011
Canine mammary tumors contain cancer stem-like cells and form spheroids with an embryonic stem cell signature.
We have investigated the presence of tentative stem-like cells in the canine mammary tumor cell line CMT-U229. This cell line is… 
Highly Cited
2009
Highly Cited
2009
OCT4 expression in human non-small cell lung cancer: implications for therapeutic intervention.
Here we investigate the expression of OCT4 human lung adenocarcinoma and bronchioloalveolar carcinoma (BAC) tumor biopsies and… 
2009
2009
The intracellular distribution of the ES cell totipotent markers OCT4 and Sox2 in adult stem cells differs dramatically according to commercial antibody used
To characterize ES cells, researchers have at their disposal a list of pluripotent markers, such as OCT4. In their quest to… 
Highly Cited
2006
Highly Cited
2006
Developmental expression of pluripotency determining factors in caprine embryos: Novel pattern of NANOG protein localization in the nucleolus
Transcription factors, POU5F1/OCT4 and NANOG, whose expression is restricted to the inner cell mass (ICM) in mouse and human… 
Highly Cited
2006
Highly Cited
2006
Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene.
Highly Cited
2005
Highly Cited
2005
Analysis of Esg1 Expression in Pluripotent Cells and the Germline Reveals Similarities with Oct4 and Sox2 and Differences Between Human Pluripotent Cell Lines
Establishment of pluripotent epiblast cells is a critical event during early mammalian development because all somatic lineages… 
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