PLK1 gene

Known as: PLK1, PLK, SERINE/THREONINE PROTEIN KINASE 13 
This gene plays a role in mitotic regulation.
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
We previously reported the phenotype of depletion of polo-like kinase 1 (Plk1) using RNA interference (RNAi) and showed that p53… (More)
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Highly Cited
2004
Highly Cited
2004
We have found that key mitotic regulators show distinct patterns of degradation during exit from mitosis in human cells. Using a… (More)
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Highly Cited
2004
Highly Cited
2004
The cohesin complex is a central player in sister chromatid cohesion, a process that ensures the faithful segregation of… (More)
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Highly Cited
2003
Highly Cited
2003
PLK (polo-like kinase), the human counterpart of polo in Drosophila melanogaster and of CDC5 in Saccharomyces cerevisiae, belongs… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Expression of polo-like kinase-1 (PLK1), which has several functions in mitotic progression, is elevated in a broad… (More)
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Highly Cited
2002
Highly Cited
2002
The mammalian polo-like kinase (Plk) plays a critical role in M-phase progression. Plk is phosphorylated and activated by an… (More)
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Highly Cited
2002
Highly Cited
2002
The cyclosome/anaphase-promoting complex is a multisubunit ubiquitin ligase that targets for degradation mitotic cyclins and some… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND During oocyte maturation in Xenopus, progesterone induces entry into meiosis I, and the M phases of meiosis I and II… (More)
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Highly Cited
1997
Highly Cited
1997
The human protein kinase Plk1, a member of the polo-like kinase family, is known to function at mitosis. Here we show that the… (More)
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Highly Cited
1996
Highly Cited
1996
Mammalian polo-like kinase 1 (Plk1) is structurally related to the polo gene product of Drosophila melanogaster, Cdc5p of… (More)
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