PLK1 protein, human

Known as: Serine/Threonine-Protein Kinase PLK1, Serine/Threonine-Protein Kinase 13, Polo-Like Kinase 
Serine/threonine-protein kinase PLK1 (603 aa, ~68 kDa) is encoded by the human PLK1 gene. This protein is involved in protein phosphorylation and the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
During cell division, chromosome segregation is orchestrated by the interaction of spindle microtubules with the centromere… (More)
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Review
2006
Review
2006
Human polo-like kinase 1 (PLK1) is essential during mitosis and in the maintenance of genomic stability. PLK1 is overexpressed in… (More)
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Highly Cited
2005
Highly Cited
2005
GRASP65, a structural protein of the Golgi apparatus, has been linked to the sensing of Golgi structure and the integration of… (More)
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Highly Cited
2005
Highly Cited
2005
Shugoshin (Sgo) proteins constitute a conserved protein family defined as centromeric protectors of Rec8-containing cohesin… (More)
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Highly Cited
2005
Highly Cited
2005
Alveolar macrophages (AMs) avidly bind and ingest inhaled environmental particles and bacteria. To identify the particle binding… (More)
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Highly Cited
2004
Highly Cited
2004
Progression through mitosis requires activation of cyclin B/Cdk1 and its downstream targets, including Polo-like kinase and the… (More)
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Highly Cited
2004
Highly Cited
2004
Wee1, the Cdc2 inhibitory kinase, needs to be down-regulated at the onset of mitosis to ensure rapid activation of Cdc2… (More)
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Highly Cited
2003
Highly Cited
2003
Plk1 (Polo-like kinase 1), an evolutionarily conserved serine/threonine kinase, is crucially involved in multiple events during… (More)
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Highly Cited
2003
Highly Cited
2003
We have investigated the function of mitotic kinesin-like protein (MKlp) 2, a kinesin localized to the central spindle, and… (More)
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Highly Cited
1995
Highly Cited
1995
PLK (STPK13) encodes a murine protein kinase closely related to those encoded by the Drosophila melanogaster polo gene and the… (More)
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