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PLIN2 gene

Known as: PLIN2, ADIPOSE DIFFERENTIATION-RELATED PROTEIN, ADRP 
This gene plays a role in lipid storage.
National Institutes of Health

Related topics

Related topics

4 relations
Ligand BindingLipid BindingPerilipin-2, humanperilipin 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA
ABSTRACT Lipids stored in lipid droplets are hydrolyzed via either cytosolic lipases or a selective form of macroautophagy known… 
Highly Cited
2013
Highly Cited
2013
Sprint interval and traditional endurance training increase net intramuscular triglyceride breakdown and expression of perilipin 2 and 5
Increases in aerobic capacity and intramuscular triglyceride (IMTG) utilization are well‐described adaptations to endurance… 
Highly Cited
2012
Highly Cited
2012
Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels
Type 2 diabetes is characterized by excessive lipid storage in skeletal muscle. Excessive intramyocellular lipid (IMCL) storage… 
Highly Cited
2005
Highly Cited
2005
S3-12, Adipophilin, and TIP47 Package Lipid in Adipocytes*
Animals have evolved mechanisms to maintain circulating nutrient levels when energy demands exceed feeding opportunities. Mammals… 
Highly Cited
2002
Highly Cited
2002
Functional Conservation for Lipid Storage Droplet Association among Perilipin, ADRP, and TIP47 (PAT)-related Proteins in Mammals,Drosophila, and Dictyostelium *
Intracellular neutral lipid storage droplets are essential organelles of eukaryotic cells, yet little is known about the proteins… 
Highly Cited
2002
Highly Cited
2002
Identification of an IMPDH1 mutation in autosomal dominant retinitis pigmentosa (RP10) revealed following comparative microarray analysis of transcripts derived from retinas of wild-type and Rho…
Comparative analysis of the transcriptional profiles of approximately 6000 genes in the retinas of wild-type mice with those… 
Highly Cited
2001
Highly Cited
2001
Mutations in the pre-mRNA splicing factor gene PRPC8 in autosomal dominant retinitis pigmentosa (RP13).
Retinitis pigmentosa (RP) is a genetically heterogeneous disorder characterized by progressive degeneration of the peripheral… 
Highly Cited
1998
Highly Cited
1998
Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases
Abstract We report the human DNA and protein sequence of adipophilin and its association with the surface of lipid droplets. The… 
Highly Cited
1997
Highly Cited
1997
Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein.
The adipose differentiation-related protein (ADRP) was first characterized as a mRNA induced early during adipocyte… 
Highly Cited
1992
Highly Cited
1992
Isolation and characterization of a full-length cDNA coding for an adipose differentiation-related protein.
We have previously isolated from a 1246 adipocyte cDNA library a cDNA clone called 154, corresponding to a mRNA that increases… 
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