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Perilipin-2, human

Known as: ADRP, Adipophilin, Adipose Differentiation-Related Protein 
Perilipin-2 (437 aa, ~48 kDa) is encoded by the human PLIN2 gene. This protein plays a role in cellular lipid storage
National Institutes of Health

Related topics

Related topics

6 relations
Ligand BindingLipid BindingLipid dropletLipoproteins
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Broader (1)

perilipin 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Perilipin-2 Deletion Impairs Hepatic Lipid Accumulation by Interfering with Sterol Regulatory Element-binding Protein (SREBP) Activation and Altering the Hepatic Lipidome*
Perilipin-2 (PLIN2) is a constitutively associated cytoplasmic lipid droplet coat protein that has been implicated in fatty liver… Expand
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Highly Cited
2015
Highly Cited
2015
Evaluation of Urine Aquaporin-1 and Perilipin-2 Concentrations as Biomarkers to Screen for Renal Cell Carcinoma: A Prospective Cohort Study.
IMPORTANCE Historically, early detection of small asymptomatic kidney tumors presages better patient outcome. Screening for… Expand
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2011
2011
The phospholipid monolayer associated with perilipin-enriched lipid droplets is a highly organized rigid membrane structure.
The significance of lipid droplets (LD) in lipid metabolism, cell signaling, and membrane trafficking is increasingly recognized… Expand
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2010
2010
Identification of perilipin-2 as a lipid droplet protein regulated in oocytes during maturation.
Lipid droplet proteins regulate the storage and utilisation of intracellular lipids. Evidence is emerging that oocyte lipid… Expand
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2010
2010
Modulation of lipid droplet size and lipid droplet proteins by trans-10,cis-12 conjugated linoleic acid parallels improvements in hepatic steatosis in obese, insulin-resistant rats.
The isomer-specific effects of conjugated linoleic acid (CLA) on hepatic steatosis were assessed in fa/fa Zucker rats, a model… Expand
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Highly Cited
2007
Highly Cited
2007
Adipocyte differentiation-related protein reduces the lipid droplet association of adipose triglyceride lipase and slows triacylglycerol turnovers⃞s⃞ The online version of this article (available at…
Although neutral lipid storage droplets are ubiquitous in eukaryotic cells, very little is known about how their synthesis and… Expand
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2005
2005
Drosophila Lipid Storage Droplet 2 gene (Lsd-2) is expressed and controls lipid storage in wing imaginal discs.
Lipid droplets are the major neutral lipid storage organelles in higher eukaryotes. The PAT domain proteins (Perilipin, ADRP… Expand
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Highly Cited
2001
Highly Cited
2001
TIP47 Associates with Lipid Droplets*
Most mammalian cells package neutral lipids into droplets that are surrounded by a monolayer of phospholipids and a specific set… Expand
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Review
1999
Review
1999
Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells.
Although all animal cells package and store neutral lipids in discrete intracellular storage droplets, there is little… Expand
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Highly Cited
1997
Highly Cited
1997
Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein.
The adipose differentiation-related protein (ADRP) was first characterized as a mRNA induced early during adipocyte… Expand
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