FAQ

Perilipin-2, human

Known as: ADRP, Adipophilin, Adipose Differentiation-Related Protein 
Perilipin-2 (437 aa, ~48 kDa) is encoded by the human PLIN2 gene. This protein plays a role in cellular lipid storage
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2017
051019902017

Related topics

Related topics

6 relations
Ligand BindingLipid BindingLipid dropletLipoproteins
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Broader (1)

perilipin 2

Related mentions per year

Related mentions per year

1944-2018
19401960198020002020
Perilipin-2, human
Lipoproteins
Lipid droplet
Lipid Binding
Ligand Binding
PLIN2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
CDK5 and MEKK1 mediate pro-apoptotic signalling following endoplasmic reticulum stress in an autosomal dominant retinitis pigmentosa model
Chronic stress in the endoplasmic reticulum (ER) underlies many degenerative and metabolic diseases involving apoptosis of vital… (More)
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2010
2010
Adipophilin expression in sebaceous tumors and other cutaneous lesions with clear cell histology: an immunohistochemical study of 117 cases
Adipophilin is a monoclonal antibody against a protein on the surface of intracellular lipid droplets, and it was recently shown… (More)
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2009
2009
Adipocyte differentiation-related protein and OXPAT in rat and human skeletal muscle: involvement in lipid accumulation and type 2 diabetes mellitus.
SETTING A disordered lipid metabolism is implicated in the development of skeletal muscle insulin resistance. Lipid droplet… (More)
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Highly Cited
2008
Highly Cited
2008
Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis.
Fatty change (steatosis) is the most frequent liver pathology in western countries and is caused by a broad range of disorders… (More)
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2006
2006
Up-regulation of ADRP in fatty liver in human and liver steatosis in mice fed with high fat diet.
The present study was performed to examine a role of adipose differentiation-related protein (ADRP) in the process of liver… (More)
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2005
2005
A PPAR response element regulates transcription of the gene for human adipose differentiation-related protein.
Lipid droplets are cytoplasmic organelles which serve as storage sites for neutral lipids. Adipose differentiation-related… (More)
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2005
2005
Rhodopsin maturation defects induce photoreceptor death by apoptosis: a fly model for RhodopsinPro23His human retinitis pigmentosa.
rhodopsin mutations result in autosomal dominant retinitis pigmentosa (ADRP), the most frequent being Proline-23 substitution by… (More)
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2003
2003
Adipose differentiation-related protein has two independent domains for targeting to lipid droplets.
Adipose differentiation-related protein (ADRP) is a protein found in lipid droplets of many cell types. In contrast to several… (More)
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Highly Cited
1999
Highly Cited
1999
Adipose differentiation related protein (ADRP) expressed in transfected COS-7 cells selectively stimulates long chain fatty acid uptake.
Adipose differentiation related protein (ADRP) is a 50-kDa novel protein cloned from a mouse 1246 adipocyte cDNA library, rapidly… (More)
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1991
1991
Identification of novel rhodopsin mutations associated with retinitis pigmentosa by GC-clamped denaturing gradient gel electrophoresis.
Retinitis pigmentosa (RP) is a group of disorders characterized by progressive degeneration of the outer retina, resulting in… (More)
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