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Perilipin-2, human

Known as: ADRP, Adipophilin, Adipose Differentiation-Related Protein 
Perilipin-2 (437 aa, ~48 kDa) is encoded by the human PLIN2 gene. This protein plays a role in cellular lipid storage
National Institutes of Health

Related topics

Related topics

6 relations
Ligand BindingLipid BindingLipid dropletLipoproteins
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Broader (1)

perilipin 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Dynamic Regulation of Hepatic Lipid Droplet Properties by Diet
Cytoplasmic lipid droplets (CLD) are organelle-like structures that function in neutral lipid storage, transport and metabolism… Expand
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2010
2010
Modulation of lipid droplet size and lipid droplet proteins by trans-10,cis-12 conjugated linoleic acid parallels improvements in hepatic steatosis in obese, insulin-resistant rats.
The isomer-specific effects of conjugated linoleic acid (CLA) on hepatic steatosis were assessed in fa/fa Zucker rats, a model… Expand
2005
2005
Drosophila Lipid Storage Droplet 2 gene (Lsd‐2) is expressed and controls lipid storage in wing imaginal discs
Lipid droplets are the major neutral lipid storage organelles in higher eukaryotes. The PAT domain proteins (Perilipin, ADRP… Expand
Highly Cited
2005
Highly Cited
2005
Adipocyte differentiation-related protein in human skeletal muscle: relationship to insulin sensitivity.
OBJECTIVE To determine whether adipocyte differentiation-related protein (ADRP), a lipid droplet-associated protein that binds to… Expand
Highly Cited
2004
Highly Cited
2004
Adipose differentiation-related protein and regulators of lipid homeostasis identified by gene expression profiling in the murine db/db diabetic kidney.
We investigated the molecular basis of progressive diabetic renal injury in db/db mice by profiling kidney gene expression. Using… Expand
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Highly Cited
2003
Highly Cited
2003
Microarray analysis of peroxisome proliferator-activated receptor-gamma induced changes in gene expression in macrophages.
We used a combination of expression microarray and Northern blot analyses to identify target genes for peroxisome proliferator… Expand
Highly Cited
2001
Highly Cited
2001
TIP47 Associates with Lipid Droplets*
Most mammalian cells package neutral lipids into droplets that are surrounded by a monolayer of phospholipids and a specific set… Expand
Highly Cited
2001
Highly Cited
2001
Adipophilin is a sensitive marker for lipid loading in human blood monocytes.
Adipophilin, a marker of lipid accumulation initially described in adipocytes, was recently shown to be induced in macrophage… Expand
Review
1999
Review
1999
Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells.
Although all animal cells package and store neutral lipids in discrete intracellular storage droplets, there is little… Expand
Highly Cited
1997
Highly Cited
1997
Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein.
The adipose differentiation-related protein (ADRP) was first characterized as a mRNA induced early during adipocyte… Expand
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