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PLCG1 gene

Known as: PHOSPHOLIPASE C-148, PLC-II, PLC1 
This gene is involved in both intracellular signaling and second messenger production.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Adult T cell leukemia/lymphoma (ATL) is a peripheral T cell neoplasm of largely unknown genetic basis, associated with human T… Expand
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Highly Cited
2014
Highly Cited
2014
Cutaneous T-cell lymphoma (CTCL) is a heterogeneous group of primary cutaneous T-cell lymphoproliferative processes, mainly… Expand
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Highly Cited
2014
Highly Cited
2014
Angiosarcoma is an aggressive malignancy that arises spontaneously or secondarily to ionizing radiation or chronic lymphoedema… Expand
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Highly Cited
2011
Highly Cited
2011
Despite evidence of the clustering of metabolic syndrome components, current approaches for identifying unifying genetic… Expand
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Highly Cited
2009
Highly Cited
2009
In this work we describe a forward genetic approach to identify mutations that affect blood vessel development in the zebrafish… Expand
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Highly Cited
2002
Highly Cited
2002
Mice nullizygous for Plcg1 cease growing at early to mid-gestation. An examination of carefully preserved wild-type embryos shows… Expand
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Highly Cited
1998
Highly Cited
1998
The Saccharomyces cerevisiae genes TOR1 and TOR2 encode phosphatidylinositol kinase homologs. TOR2 has two essential functions… Expand
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Highly Cited
1997
Highly Cited
1997
Several candidate genes for non-insulin-dependent diabetes mellitus (NIDDM) map on chromosome 20, including the… Expand
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Highly Cited
1995
Highly Cited
1995
Phosphoinositide-specific phospholipase C (PI-PLC) is a key signal transducing enzyme which generates the second messengers… Expand
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Highly Cited
1993
Highly Cited
1993
Using the polymerase chain reaction technique, we have isolated a gene that encodes a putative phosphoinositide-specific… Expand
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