PIK3CG wt Allele

Known as: PI3CG, PIK3, PI3K 
Human PIK3CG wild-type allele is located in the vicinity of 7q22.3 and is approximately 42 kb in length. This allele, which encodes… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
05101519972017

Papers overview

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Highly Cited
2010
Highly Cited
2010
T cell development requires phosphatidylinositol 3-kinase (PI3K) signaling with contributions from both the class IA, p110delta… (More)
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2010
2010
The PIK3 signaling pathway has been identified as one of the most important and most frequently mutated pathways in breast cancer… (More)
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Highly Cited
2008
Highly Cited
2008
The p110 isoforms of phosphoinositide 3-kinase (PI3K) are acutely regulated by extracellular stimuli. The class IA PI3K catalytic… (More)
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2007
2007
Fibrolamellar carcinomas (FLC) are a rare type of primary hepatocellular carcinoma found in younger individuals. FLC are known to… (More)
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Highly Cited
2005
Highly Cited
2005
The role of PI3K activity in T lymphocyte development is obscure because mice deficient in single PI3K catalytic subunits either… (More)
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2005
2005
A variety of genetic and inhibitor studies have shown that phosphoinositide 3-kinase gamma (PI3Kgamma) plays an essential role in… (More)
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Highly Cited
2004
Highly Cited
2004
Despite the established role for PI3Ks in cell migration, the PI3Ks involved in lymphocyte chemotaxis are poorly defined. In this… (More)
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Highly Cited
1999
Highly Cited
1999
By using purified preparations we show that nanomolar concentrations of Gbetagamma significantly stimulated lipid kinase activity… (More)
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Highly Cited
1998
Highly Cited
1998
Class I phosphoinositide 3-kinases (PI3Ks) regulate important cellular processes such as mitogenesis, apoptosis, and cytoskeletal… (More)
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Highly Cited
1997
Highly Cited
1997
Male-specific migration of cells from the mesonephric kidney into the embryonic gonad is required for testis formation in the… (More)
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