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PIK3CG gene

Known as: PIK3CG, PHOSPHATIDYLINOSITOL 3-KINASE, CATALYTIC, GAMMA, PI3K-GAMMA 
This gene is involved in cell adhesion, signal transduction and maintenance of the structural and functional integrity of epithelia.
National Institutes of Health

Related topics

Related topics

10 relations
1-Phosphatidylinositol 3-Kinase1-phosphatidylinositol-3-kinase activityCell AdhesionPIK3CA gene

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PIK3CG wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Human PI3Kγ deficiency and its microbiota-dependent mouse model reveal immunodeficiency and tissue immunopathology
Phosphatidylinositol 3-kinase-gamma (PI3Kγ) is highly expressed in leukocytes and is an attractive drug target for immune… 
2017
2017
Sequencing‐based network analysis provides a core set of gene resource for understanding kidney immune response against Edwardsiella tarda infection in Japanese flounder
2014
2014
Lack of Association between ABO, PPAP2B, ADAMST7, PIK3CG, and EDNRA and Carotid Intima-Media Thickness, Carotid Plaques, and Cardiovascular Disease in Patients with Rheumatoid Arthritis
Introduction. Rheumatoid arthritis (RA) is a polygenic disease associated with accelerated atherosclerosis and increased… 
2014
2014
Exome-wide mutation profile in benzo[a]pyrene-derived post-stasis and immortal human mammary epithelial cells.
Highly Cited
2010
Highly Cited
2010
Inferring the functional effects of mutation through clusters of mutations in homologous proteins
Inferring functional consequences is a bottleneck in high‐throughput cancer mutation discovery and genetic association studies… 
Highly Cited
2010
Highly Cited
2010
Prioritization of driver mutations in pancreatic cancer using cancer-specific high-throughput annotation of somatic mutations (CHASM)
Over 20,000 genes were recently sequenced in a series of 24 pancreatic cancers. We applied CHASM (Cancer-specific High-throughput… 
Highly Cited
2004
Highly Cited
2004
Association analysis between longevity in the Japanese population and polymorphic variants of genes involved in insulin and insulin-like growth factor 1 signaling pathways
Highly Cited
2003
Highly Cited
2003
Association of INPP1, PIK3CG, and TSC2 gene variants with autistic disorder: implications for phosphatidylinositol signalling in autism
Epidemiological studies have shown that about 43–86% of individuals with tuberous sclerosis complex have a pervasive… 
Highly Cited
2002
Highly Cited
2002
Down-regulation of PIK3CG, a catalytic subunit of phosphatidylinositol 3-OH kinase, by CpG hypermethylation in human colorectal carcinoma.
PURPOSE Premature death associated with colorectal adenocarcinoma occurs in PIK3CG(-/-) mice and overexpression of PIK3CG in… 
2002
2002
Genomic structure of the PIK3CG gene on chromosome band 7q22 and evaluation as a candidate myeloid tumor suppressor.
PIK3CG, which encodes the catalytic subunit p110 gamma of phosphoinositide 3-OH-kinase-gamma (PI3K gamma), has been assigned to… 
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