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PHB gene

Known as: Prohibitin Gene, PROHIBITIN, PHB 
This gene plays a role in the negative regulation of both apoptosis and cell proliferation.
National Institutes of Health

Related topics

Related topics

8 relations
DNA ReplicationInhibition of Cell ProliferationNegative Regulation of ApoptosisPHBP1 gene

Papers overview

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Highly Cited
2011
Highly Cited
2011
Hepatocarcinogenesis in Hepatitis C: HCV Shrewdly Exacerbates Oxidative Stress by Modulating both Production and Scavenging of Reactive Oxygen Species
Persistent infection with hepatitis C virus (HCV) is a major risk for the development of hepatocellular carcinoma (HCC). One of… 
Highly Cited
2010
Highly Cited
2010
Prohibitins Are Required for Cancer Cell Proliferation and Adhesion
Prohibitin 1 (PHB1) is a highly conserved protein that together with its homologue prohibitin 2 (PHB2) mainly localizes to the… 
Highly Cited
2007
Highly Cited
2007
Spatio-temporal characterization of polyhydroxybutyrate accumulation in sugarcane.
We report here the results from a glasshouse trial of several transgenic sugarcane (Saccharum spp. hybrids) lines accumulating… 
Highly Cited
2007
Highly Cited
2007
Apoptosis of rat granulosa cells after staurosporine and serum withdrawal is suppressed by adenovirus-directed overexpression of prohibitin.
Prohibitin (Phb1) is a highly conserved mitochondrial protein that is associated with granulosa cell differentiation, atresia… 
Highly Cited
2006
Highly Cited
2006
Prohibitin Facilitates Cellular Senescence by Recruiting Specific Corepressors To Inhibit E2F Target Genes
ABSTRACT Prohibitin is a growth regulatory gene that has pleiotropic functions in the nucleus, mitochondria, and cytoplasmic… 
Highly Cited
2006
Highly Cited
2006
Loss of transgelin in repeated bouts of ulcerative colitis‐induced colon carcinogenesis
Though ulcerative colitis (UC)‐associated colon cancer develops from dysplastic lesions caused by chronic inflammation, the… 
Highly Cited
2005
Highly Cited
2005
The Stomatin/Prohibitin/Flotillin/HflK/C Domain of Flotillin-1 Contains Distinct Sequences That Direct Plasma Membrane Localization and Protein Interactions in 3T3-L1 Adipocytes*
Flotillin-1 is a lipid raft-associated protein that has been implicated in various cellular processes. We examined the… 
2003
2003
Physical properties of microbial polythioesters: characterization of poly(3-mercaptoalkanoates) synthesized by engineered Escherichia coli.
Physical properties of chiral poly(thioesters), PTEs, prepared by engineered Escherichia coli, were examined by GPC, 13C CP/MAS… 
Highly Cited
1998
Highly Cited
1998
Changes in the nucleolar and coiled body compartments precede lamina and chromatin reorganization during fibre cell denucleation in the bovine lens.
Highly Cited
1995
Highly Cited
1995
Prohibitin, an antiproliferative protein, is localized to mitochondria
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