Skip to search formSkip to main contentSkip to account menu

PGGT1B wt Allele

Known as: BGGI, GGTI, Protein Geranylgeranyltransferase Type I, Beta Subunit wt Allele 
Human PGGT1B wild-type allele is located in the vicinity of 5q22.3 and is approximately 51 kb in length. This allele, which encodes geranylgeranyl… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Isoprenylation is a posttranslational modification that transfers farnesyl pyrophosphate (FPP) or geranylgeranyl pyrophosphate… 
2013
2013
Glioblastoma multiforme is a highly migratory and invasive brain tumor in which hypoxia inducible factor-1α (HIF-1α) plays… 
2012
2012
Protein farnesyltransferase (FTase) inhibitors, generally called “FTIs,” block the farnesylation of prelamin A, inhibiting the… 
2011
2011
PurposeGeranylgeranyltransferase I is required for the prenylation of the small GTPases. The effect of GGTase I inhibitors (GGTIs… 
Highly Cited
2009
Highly Cited
2009
ABSTRACT We describe the design of a potent and selective peptidomimetic inhibitor of geranylgeranyltransferase I (GGTI), GGTI… 
2006
2006
Progesterone receptor (PR) stimulation promotes survival in human and rat periovulatory granulosa cells. PR antagonists, Org… 
2005
2005
The high incidence of activating RAS mutations, coupled with accumulating evidence linking RAS to multiple myeloma (MM… 
2002
2002
Here we demonstrate that the geranylgeranyltransferase-I inhibitor GGTI-298 inhibits the RhoB pathway and disrupts stress fiber… 
2001
2001
Farnesyl:protein transferase (FPTase) inhibitors (FTIs) were originally developed as potential anticancer agents targeting the…