PGGT1B wt Allele

Known as: BGGI, GGTI, Protein Geranylgeranyltransferase Type I, Beta Subunit wt Allele 
Human PGGT1B wild-type allele is located in the vicinity of 5q22.3 and is approximately 51 kb in length. This allele, which encodes geranylgeranyl… (More)
National Institutes of Health

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Topic mentions per year

2003-2010
01220032010

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2011
2011
Smooth muscle cells promote fibroproliferative airway remodeling in asthma, and transforming growth factor β1 (TGFβ1) is a key… (More)
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2010
2010
BACKGROUND Suboptimal activation of T lymphocytes by melanoma cells is often due to the defective expression of class I major… (More)
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2010
2010
Geranylgeranyltransferase I is required for the prenylation of the small GTPases. The effect of GGTase I inhibitors (GGTIs) on… (More)
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2008
2008
Protein geranylgeranylation is critical for the function of a number of proteins such as RhoA, Rac, and Rab. Protein… (More)
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2003
2003
As deregulation of RAS signaling is important in the pathogenesis of myeloid leukemias, molecular targeting of RAS signaling may… (More)
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