Isoprenylation

Known as: Isoprenylation Process, Prenylation 
The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added. [GOC:di, PMID:18029206, PMID… (More)
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Protein isoprenylation refers to the covalent attachment of a 15-carbon farnesyl or 20-carbon geranylgeranyl moiety to a cysteine… (More)
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Review
2009
Review
2009
Prenylation plays a major role in the diversification of aromatic natural products, such as phenylpropanoids, flavonoids, and… (More)
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Highly Cited
2007
Highly Cited
2007
Epidemiological evidence suggests that long term treatment with hydroxymethylglutaryl-CoA reductase inhibitors, or statins… (More)
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Highly Cited
1999
Highly Cited
1999
Recently, advances have been made in understanding the molecular mechanisms by which bisphosphonate drugs inhibit bone resorption… (More)
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Highly Cited
1994
Highly Cited
1994
Mature A- and B-type lamins differ in the extent to which they interact with the nuclear membrane and thus represent an… (More)
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Highly Cited
1994
Highly Cited
1994
The monoterpene d-limonene inhibits the post-translational isoprenylation of p21ras and other small G proteins, a mechanism that… (More)
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Highly Cited
1991
Highly Cited
1991
Recent evidence suggests that the conserved COOH-terminal CaaX motif of nuclear lamins may play a role in targeting newly… (More)
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Highly Cited
1991
Highly Cited
1991
Limonene has chemotherapeutic activity against chemically induced rat mammary carcinomas, many of which contain activated ras… (More)
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Highly Cited
1990
Highly Cited
1990
It has been reported that when 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors are utilized for treatment of… (More)
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Review
1990
Review
1990
Isoprenylation is a posttranslational modification that involves the formation of thioether bonds between cysteine and isoprenyl… (More)
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