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PGGT1B gene

Known as: PGGT1B, BGGI, Protein Geranylgeranyltransferase Type I, Beta Subunit Gene 
This gene is plays a role in subcellular protein targeting and the post-translational modification of certain proteins.
National Institutes of Health

Related topics

Related topics

5 relations
IsoprenylationPGGT1B protein, humanPost-Translational Protein Processingintracellular protein transport

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PGGT1B wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
32.2 ABNORMALITIES OF SYNAPTIC PROTEOMES IN SCHIZOPHRENIA
Abstract Background The human brain is comprised of billions of neurons that form networks of connections within and between… 
2018
2018
32.1 MECHANISMS OF ABNORMAL POSTTRANSLATIONAL PROTEIN PROCESSING IN SCHIZOPHRENIA BRAIN
Abstract Background Molecular disturbances of neurotransmitter systems have long been held to be a core feature of the… 
2018
2018
Assessment of Protein Prenylation Pathway in Multiple Sclerosis Patients
Multiple sclerosis (MS) is a chronic inflammatory disorder with several genetic and environmental factors being implicated in its… 
2015
2015
Nanoformulation of Geranylgeranyltransferase-I Inhibitors for Cancer Therapy: Liposomal Encapsulation and pH-Dependent Delivery to Cancer Cells
Small molecule inhibitors against protein geranylgeranyltransferase-I such as P61A6 have been shown to inhibit proliferation of a… 
2012
2012
Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24
Protein farnesyltransferase (FTase) inhibitors, generally called “FTIs,” block the farnesylation of prelamin A, inhibiting the… 
2008
2008
In-vivo effects of simvastatin and rosuvastatin on global gene expression in peripheral blood leucocytes in a human inflammation model
Objective To gain insight into molecular mechanisms of anti-inflammatory effects of statins, we have studied global gene… 
2001
2001
Preclinical Models Geranylgeranyl : Protein Transferase Inhibitor Combinations in Evaluation of Farnesyl : Protein Transferase and Updated
Farnesyl:protein transferase (FPTase) inhibitors (FTIs) were originally developed as potential anticancer agents targeting the… 
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