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PGGT1B gene

Known as: PGGT1B, BGGI, Protein Geranylgeranyltransferase Type I, Beta Subunit Gene 
This gene is plays a role in subcellular protein targeting and the post-translational modification of certain proteins.
National Institutes of Health

Related topics

Related topics

5 relations
IsoprenylationPGGT1B protein, humanPost-Translational Protein Processingintracellular protein transport

Narrower (1)

PGGT1B wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Systemic Investigation of Promoter-wide Methylome and Genome Variations in Gout
Current knowledge of gout centers on hyperuricemia. Relatively little is known regarding the pathogenesis of gouty inflammation… 
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2019
2019
Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice.
BACKGROUND AND AIMS It is not clear how regulation of T-cell function is altered during development of inflammatory bowel… 
2019
2019
Identification and Validation of Novel Reference Genes in Acute Lymphoblastic Leukemia for Droplet Digital PCR
Droplet digital PCR is the most robust method for absolute nucleic acid quantification. However, RNA is a very versatile molecule… 
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2018
2018
32.2 ABNORMALITIES OF SYNAPTIC PROTEOMES IN SCHIZOPHRENIA
Abstract Background The human brain is comprised of billions of neurons that form networks of connections within and between… 
2018
2018
Assessment of Protein Prenylation Pathway in Multiple Sclerosis Patients
Multiple sclerosis (MS) is a chronic inflammatory disorder with several genetic and environmental factors being implicated in its… 
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2018
2018
32.1 MECHANISMS OF ABNORMAL POSTTRANSLATIONAL PROTEIN PROCESSING IN SCHIZOPHRENIA BRAIN
Abstract Background Molecular disturbances of neurotransmitter systems have long been held to be a core feature of the… 
2015
2015
Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis
BackgroundKey effector(s) of mutated KRAS in lung cancer progression and metastasis are unknown. Here we investigated the role of… 
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Highly Cited
2013
Highly Cited
2013
Therapeutic effects of microRNA-582-5p and -3p on the inhibition of bladder cancer progression.
Many reports have indicated that the abnormal expression of microRNAs (miRNAs) is associated with the progression of disease and… 
2009
2009
Genetic mapping of the sex-linked barring gene in the chicken.
The sex-linked barring gene of the chicken (Gallus gallus), first identified in 1908, produces an alternating pattern of white… 
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Highly Cited
2007
Highly Cited
2007
Geranylgeranyltransferase I Inhibitors Target RalB To Inhibit Anchorage-Dependent Growth and Induce Apoptosis and RalA To Inhibit Anchorage-Independent Growth
ABSTRACT Geranylgeranyltransferase I inhibitors (GGTIs) are presently undergoing advanced preclinical studies and have been shown… 
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