PF4 gene

Known as: SMALL INDUCIBLE CYTOKINE SUBFAMILY B, MEMBER 4, Platelet Factor 4 (Chemokine (C-X-C Motif) Ligand 4) Gene, CHEMOKINE, CXC MOTIF, LIGAND 4 
This gene plays a role in platelet aggregation and promotes blood coagulation.
National Institutes of Health

Papers overview

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2011
2011
The P2Y12 receptor plays a crucial role in the regulation of platelet activation by several agonists, which is irreversibly… (More)
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Highly Cited
2008
Highly Cited
2008
Cerebral malaria (CM) is a major complication of Plasmodium falciparum infection in children. The pathogenesis of CM involves… (More)
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Highly Cited
2004
Highly Cited
2004
The chemokines platelet factor 4 (PF4) and RANTES (regulated on activation normal T cell expressed and secreted) are secreted by… (More)
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Review
2001
Review
2001
The role of platelets as inflammatory cells is demonstrated by the fact that they can release many growth factors and… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND No data exist regarding the inter-laboratory reproducibility of the heparin-induced-platelet-activation (HIPA) test… (More)
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Highly Cited
1999
Highly Cited
1999
In the absence of the hematopoietic transcription factor GATA-1, mice develop thrombocytopenia and an increased number of… (More)
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1994
1994
The crystal structure of human platelet factor 4 (PF4) has been solved to a resolution of 2.4 A by molecular replacement and… (More)
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1993
1993
The possible involvement of platelets in bronchial asthma was investigated under three different conditions: (1) chronic asthma… (More)
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Highly Cited
1985
Highly Cited
1985
We have developed a model of acute Dacron graft thrombosis in baboons in order to assess platelet alterations secondary to… (More)
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1985
1985
Platelets are believed to play a role in the pathogenesis of atherosclerosis and of the vascular obstruction that causes the… (More)
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