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PEMT gene

Known as: PEMT2, PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE, PEMPT 
This gene plays a role in phosphatidylethanolamine metabolism.
National Institutes of Health

Related topics

Related topics

6 relations
MethylationPhosphatidylcholine BiosynthesisPhosphatidylethanolamine N-MethyltransferasePhospholipid Metabolism

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PEMT wt Allele

Papers overview

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2020
2020
Associations between folate and choline intake, homocysteine metabolism, and genetic polymorphism of MTHFR, BHMT and PEMT in healthy pregnant Polish women.
AIM Physiological homocysteine (Hcy) concentrations depend on several factors, both dietary (including folate and choline intake… 
2018
2018
PEMT rs12325817 and PCYT1A rs7639752 polymorphisms are associated with betaine but not choline concentrations in pregnant women.
2017
2017
Genetic Variation in Choline-Metabolizing Enzymes Alters Choline Metabolism in Young Women Consuming Choline Intakes Meeting Current Recommendations
Single nucleotide polymorphisms (SNPs) in choline metabolizing genes are associated with disease risk and greater susceptibility… 
2016
2016
Dietary choline and betaine intake, choline-metabolising genetic polymorphisms and breast cancer risk: a case–control study in China
Abstract Choline and betaine are essential nutrients involved in one-carbon metabolism and have been hypothesised to affect… 
Highly Cited
2014
Highly Cited
2014
The Concentration of Phosphatidylethanolamine in Mitochondria Can Modulate ATP Production and Glucose Metabolism in Mice
Phosphatidylethanolamine (PE) N-methyltransferase (PEMT) catalyzes the synthesis of phosphatidylcholine (PC) in the liver. Mice… 
Highly Cited
2014
Highly Cited
2014
Identification of new genetic polymorphisms that alter the dietary requirement for choline and vary in their distribution across ethnic and racial groups
Effect alleles (alleles with a polymorphism that is associated with the effect being measured) in a small number of single… 
2014
2014
Associations of Common Variants in Methionine Metabolism Pathway Genes with Plasma Homocysteine and the Risk of Type 2 Diabetes in Han Chinese
Background/Aims: An association of genetic variants of homocysteine (Hcy) metabolic genes with type 2 diabetes mellitus (T2DM… 
Highly Cited
2009
Highly Cited
2009
Associations of folate and choline metabolism gene polymorphisms with orofacial clefts
Background Non-syndromic isolated cleft lip with or without cleft palate (NCL/P) is a common congenital anomaly in humans, the… 
2003
2003
Expression of Phosphatidylethanolamine N-Methyltransferase in Human Hepatocellular Carcinomas
Objective: Hepatic phosphatidylethanolamine is converted into phosphatidylcholine by the enzyme phosphatidylethanolamine N… 
Review
1998
Review
1998
Roles for the methylation of phosphatidylethanolamine.
The methylation of phosphatidylethanolamine is an auxiliary pathway for phosphatidylcholine biosynthesis in liver. Two forms of… 
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