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Phosphatidylcholine Biosynthesis

Known as: phosphatidylcholine biosynthetic process, phosphatidylcholine anabolism, phosphatidylcholine synthesis 
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. Choline kinase is the initial enzyme that produces… Expand
National Institutes of Health

Papers overview

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Review
2007
Review
2007
This report is a summary of a symposium on the role of S-adenosylmethionine (SAM), betaine, and folate in the treatment of… Expand
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Highly Cited
2005
Highly Cited
2005
Phosphatidylethanolamine N‐methyltransferase (PEMT) catalyzes phosphatidylcholine synthesis. PEMT knockout mice have fatty livers… Expand
Highly Cited
2004
Highly Cited
2004
Plasmodium falciparum is the causative agent of the most severe form of human malaria. The rapid multiplication of the parasite… Expand
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Highly Cited
2001
Highly Cited
2001
Liposomes were prepared by stepwise extrusion through 5, 1, 0.4, 0.2, 0.1 and 0.05 microm pore sizes using two different filter… Expand
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Highly Cited
1999
Highly Cited
1999
In addition to the CDP-choline pathway for phosphatidylcholine (PC) synthesis, the liver has a unique phosphatidylethanolamine… Expand
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Highly Cited
1999
Highly Cited
1999
Induction of apoptosis in HL-60 cells, using a variety of cytotoxic drugs, resulted, in all cases, in inhibition of CDP-choline:1… Expand
Highly Cited
1999
Highly Cited
1999
Phosphatidylcholine is a major lipid of eukaryotic membranes, but found in only few prokaryotes. Enzymatic methylation of… Expand
Review
1992
Review
1992
  • R. Wurtman
  • Trends in Neurosciences
  • 1992
  • Corpus ID: 25036808
The unique propensity of cholinergic neurons to use choline for two purposes--ACh and membrane phosphatidylcholine synthesis--may… Expand
Highly Cited
1988
Highly Cited
1988
  • Z. Yao, D. Vance
  • The Journal of biological chemistry
  • 1988
  • Corpus ID: 25198626
Hepatocytes obtained from rats fed a choline-deficient diet for 3 days were cultured in a medium +/- choline (100 microM) or… Expand
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Highly Cited
1975
Highly Cited
1975
The effects of choline, ethanolamine and its N-methyl analogs, different fatty acids, and L-methionine on phospholipid… Expand