Phosphatidylcholine Biosynthesis

Known as: phosphatidylcholine biosynthetic process, phosphatidylcholine anabolism, phosphatidylcholine synthesis 
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. Choline kinase is the initial enzyme that produces… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1956-2017
0102019562016

Papers overview

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2009
2009
Phosphatidylcholine (PC), or lecithin, is the major phospholipid in eukaryotic membranes, whereas only 10% of all bacteria are… (More)
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Highly Cited
2004
Highly Cited
2004
When the protein folding capacity of the endoplasmic reticulum (ER) is challenged, the unfolded protein response (UPR) maintains… (More)
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2004
2004
The genomes of Treponema denticola and Treponema pallidum contain a gene, licCA, which is predicted to encode a fusion protein… (More)
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Highly Cited
1999
Highly Cited
1999
In addition to the CDP-choline pathway for phosphatidylcholine (PC) synthesis, the liver has a unique phosphatidylethanolamine… (More)
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1999
1999
Induction of apoptosis in HL-60 cells, using a variety of cytotoxic drugs, resulted, in all cases, in inhibition of CDP-choline:1… (More)
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1997
1997
Phospholipids are the major components of cell membranes and are required for cellular growth. We studied membrane… (More)
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Highly Cited
1996
Highly Cited
1996
We have investigated the cell death of a Chinese hamster ovary mutant (MT-58) with a thermo-sensitive CTP:phosphocholine… (More)
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Highly Cited
1995
Highly Cited
1995
The regulation of the CDP-choline pathway of phosphatidylcholine synthesis at the CTP:phosphocholine cytidylyltransferase (CT… (More)
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1994
1994
Atheroma macrophages accumulate large amounts of free cholesterol (FC) as well as cholesteryl ester (CE). An important adaptive… (More)
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Highly Cited
1988
Highly Cited
1988
Hepatocytes obtained from rats fed a choline-deficient diet for 3 days were cultured in a medium +/- choline (100 microM) or… (More)
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