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PDGF AA

Known as: PDGF-AA, Platelet-Derived Growth Factor-AA 
A disulfide-linked homodimeric protein complex comprised of 2 platelet-derived growth factor subunit A proteins. This dimeric growth factor binds to… 
National Institutes of Health

Related topics

Related topics

7 relations
Cell ProliferationExtracellular SpaceGrowth FactorPDGFA protein, human

Broader (1)

platelet-derived growth factor A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Corneal neovascularization and the utility of topical VEGF inhibition: ranibizumab (Lucentis) vs bevacizumab (Avastin).
Highly Cited
2010
Highly Cited
2010
Directional Cell Migration and Chemotaxis in Wound Healing Response to PDGF-AA are Coordinated by the Primary Cilium in Fibroblasts
Cell motility and migration play pivotal roles in numerous physiological and pathophysiological processes including development… 
Highly Cited
1998
Highly Cited
1998
Expression of growth factors, growth‐inhibiting factors, and their receptors in invasive breast cancer. II: Correlations with proliferation and angiogenesis
Growth factors may play an important role in tumour growth and angiogenesis by their influence on tumour cell proliferation or… 
Highly Cited
1996
Highly Cited
1996
PDGF isoform-induced proliferation and receptor expression in human cultured airway smooth muscle cells.
The effect of recombinant platelet-derived growth factor (PDGF) isoforms (PDGF-AA, -BB and -AB) on mitogenesis of human cultured… 
Highly Cited
1995
Highly Cited
1995
Platelet‐derived Growth Factor
Highly Cited
1994
Highly Cited
1994
Expression of fibrogenic cytokines in rat small intestine after fractionated irradiation.
Highly Cited
1994
Highly Cited
1994
TGF-beta promotes proliferation of cultured SMC via both PDGF-AA-dependent and PDGF-AA-independent mechanisms.
Transforming growth factor-beta 1 (TGF-beta 1) has been implicated in mediating smooth muscle cell (SMC) growth after vascular… 
Highly Cited
1993
Highly Cited
1993
Mitogenic effect of transforming growth factor‐β1 on human ito cells in culture: Evidence for mediation by endogenous platelet‐derived growth factor
We assessed the effect of transforming growth factor‐β1 on the proliferation of human Ito cells. Ito cells in their… 
Highly Cited
1989
Highly Cited
1989
Interleukin-1 mitogenic activity for fibroblasts and smooth muscle cells is due to PDGF-AA.
Both interleukin-1 (IL-1) and platelet-derived growth factor (PDGF) induce proliferation of cultured fibroblasts and smooth… 
Highly Cited
1988
Highly Cited
1988
Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types.
The binding of the three dimeric forms of platelet‐derived growth factor (PDGF), PDGF‐AA, PDGF‐AB and PDGF‐BB, to human… 
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