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PDCD4 gene

Known as: Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) Gene, programmed cell death 4 (neoplastic transformation inhibitor), NEOPLASTIC TRANSFORMATION INHIBITOR 
This gene may be involved in apoptosis and translation.
National Institutes of Health

Related topics

Related topics

7 relations
ApoptosisCell AgingProgrammed Cell Death Protein 4Transcriptional Repression

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PDCD4 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Inhibition of miR-141 reverses cisplatin resistance in non-small cell lung cancer cells via upregulation of programmed cell death protein 4.
OBJECTIVE MicroRNAs are a class of essential regulators in cancer, and previous studies have shown that miR-141 is a tumor… 
Highly Cited
2015
Highly Cited
2015
MicroRNA-21, up-regulated by arsenite, directs the epithelial-mesenchymal transition and enhances the invasive potential of transformed human bronchial epithelial cells by targeting PDCD4.
2014
2014
Histone demethylase RBP2 decreases miR-21 in blast crisis of chronic myeloid leukemia
Chronic myeloid leukemia in the blastic phase (CML-BP) responds poorly to clinical treatments and is usually fatal. In this study… 
2013
2013
Loss of PDCD4 contributes to enhanced chemoresistance in Glioblastoma Multiforme through de-repression of Bcl-xL translation
Glioblastoma multiforme (GBM) is the most common and aggressive form of tumor of the central nervous system. Despite significant… 
Highly Cited
2012
Highly Cited
2012
PDCD4 expression inversely correlated with miR-21 levels in gastric cancers
PurposeThe specific aim of this study was to investigate whether the PDCD4 gene is involved in the development and progression of… 
Highly Cited
2011
Highly Cited
2011
microRNA-499-5 p promotes cellular invasion and tumor metastasis in colorectal cancer by targeting FOXO 4 and PDCD 4
MicroRNAs (miRNAs) regulate tumor progression and invasion via direct interaction with target messenger RNAs (mRNAs). We defined… 
Highly Cited
2011
Highly Cited
2011
The negative costimulatory molecule PD‐1 modulates the balance between immunity and tolerance via miR‐21
Disruption of the programmed death‐1 (PD‐1) pathway leads to breakdown of peripheral tolerance and initiation of autoimmunity… 
Highly Cited
2011
Highly Cited
2011
PDCD4 nuclear loss inversely correlates with miR-21 levels in colon carcinogenesis
Programmed cell death 4 (PDCD4) has recently been demonstrated to be a new tumor suppressor gene involved in colon carcinogenesis… 
Highly Cited
2008
Highly Cited
2008
Suppression of Programmed Cell Death 4 (PDCD4) Protein Expression by BCR-ABL-regulated Engagement of the mTOR/p70 S6 Kinase Pathway*
There is accumulating evidence that mammalian target of rapamycin (mTOR)-activated pathways play important roles in cell growth… 
1999
1999
Assignment1 of the programmed cell death 4 gene (PDCD4) to human chromosome band 10q24 by in situ hybridization
H731 (PDCD4) was isolated from a human glioma cDNA library by screening with a monoclonal antibody, Pr-28, which recognizes a… 
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