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PDCD4 gene

Known as: Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) Gene, programmed cell death 4 (neoplastic transformation inhibitor), NEOPLASTIC TRANSFORMATION INHIBITOR 
This gene may be involved in apoptosis and translation.
National Institutes of Health

Related topics

Related topics

7 relations
ApoptosisCell AgingProgrammed Cell Death Protein 4Transcriptional Repression

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PDCD4 wt Allele

Papers overview

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2018
2018
Inhibition of cell migration and invasion and promotion of cell apoptosis by overexpression of programmed cell death 4 (PDCD4) in cervical cancer Siha cells.
Cervical cancer has been one of the leading causes of cancer-related deaths among women worldwide. However, few targeted drugs… 
2017
2017
Role of the TGFβ/PDCD4/AP-1 Signaling Pathway in Nasopharyngeal Carcinoma and Its Relationship to Prognosis
Background: The objective of the present study was to evaluate the role of the TGFβ/PDCD4/AP-1 pathway in nasopharyngeal… 
2015
2015
Cell Density-Dependent Upregulation of PDCD4 in Keratinocytes and Its Implications for Epidermal Homeostasis and Repair
Programmed cell death 4 (PDCD4) is one multi-functional tumor suppressor inhibiting neoplastic transformation and tumor invasion… 
2015
2015
ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism
Programmed cell death 4 (PDCD4) is a tumour suppressor implicated in cancer development and progression and was recently… 
2013
2013
Rapamycin Enhances TNF-α-Induced Secretion of IL-6 and IL-8 through Suppressing PDCD4 Degradation in Orbital Fibroblasts
Purpose: To investigate the effects of rapamycin on the TNF-α-induced secretion of interleukin-6 (IL-6) and IL-8 in orbital… 
2012
2012
An essential role of PDCD4 in progression and malignant proliferation of gastrointestinal stromal tumors
Programmed cell death 4 (PDCD4) is a tumor suppressor that can inhibit tumorigenesis by suppressing activator protein (AP)-1… 
2010
2010
Programmed cell death 4 (PDCD4) expression during multistep Barrett's carcinogenesis
Aim To test the contribution of programmed cell death 4 (PDCD4) tumour suppressor gene in Barrett's carcinogenesis. Methods PDCD4… 
Highly Cited
2008
Highly Cited
2008
Suppression of Programmed Cell Death 4 (PDCD4) Protein Expression by BCR-ABL-regulated Engagement of the mTOR/p70 S6 Kinase Pathway*
There is accumulating evidence that mammalian target of rapamycin (mTOR)-activated pathways play important roles in cell growth… 
1999
1999
Assignment1 of the programmed cell death 4 gene (PDCD4) to human chromosome band 10q24 by in situ hybridization
H731 (PDCD4) was isolated from a human glioma cDNA library by screening with a monoclonal antibody, Pr-28, which recognizes a… 
1998
1998
Expression and identification of H731 gene product in hela cells
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