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Programmed Cell Death Protein 4

Known as: Neoplastic Transformation Inhibitor Protein, Nuclear Antigen H731-Like, Protein 197/15a 
Programmed cell death protein 4 (469 aa, ~52 kDa) is encoded by the human PDCD4 gene. This protein may be involved in the regulation of both… 
National Institutes of Health

Related topics

Related topics

11 relations
ApoptosisApoptosis Regulatory ProteinsCell AgingGenes, Regulator

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Involvement of androgen receptor (AR)/microRNA-21 axis in hypoxia/reoxygenation-induced apoptosis of mouse renal tubular epithelial cells.
The function of androgen receptor (AR)/microRNA-21 (miR-21) axis in tumor development was well investigated. However, the roles… 
2018
2018
Upregulation of miR-96 promotes radioresistance in glioblastoma cells via targeting PDCD4.
Glioblastoma multiforme (GBM) is the most deadly brain tumor, and it is characterized by extremely poor therapeutic response and… 
2018
2018
miR-181a-5p Regulates TNF-α and miR-21a-5p Influences Gualynate-Binding Protein 5 and IL-10 Expression in Macrophages Affecting Host Control of Brucella abortus Infection
Brucella abortus is a Gram-negative intracellular bacterium that causes a worldwide zoonosis termed brucellosis, which is… 
Review
2018
Review
2018
The Bidirectional Effects of Arsenic on miRNA-21: A Systematic Review and Meta-analysis.
  • Jia LiuQ. Niu R. Ma
  • Biomedical and environmental sciences : BES
  • 2018
  • Corpus ID: 53100180
OBJECTIVE Arsenic is a metalloid environmental carcinogen involved in the occurrence and development of many cancers. miRNA-21… 
2017
2017
Depletion of the mRNA translation initiation inhibitor, programmed cell death protein 4 (PDCD4), impairs L6 myotube formation
The mechanistic (mammalian) target of rapamycin complex 1 (mTORC1) signaling is vital for optimal muscle mass and function… 
2017
2017
miR-21 attenuates contrast-induced renal cell apoptosis by targeting PDCD4
Contrast medium (CM) is widely used in cardiac catheterization; however, it may induce acute kidney injury or renal failure… 
2015
2015
Up-regulation of MicroRNA-21 Mediates Isoflurane-induced Protection of Cardiomyocytes
Background:Anesthetic cardioprotection reduces myocardial infarct size after ischemia–reperfusion injury. Currently, the role of… 
2015
2015
Das programmed cell death protein 4 (pdcd4) wirkt in neuroendokrinen Tumorzellen als Tumorsuppressorgen
2014
2014
[Signal transducer and activator of transcription-3 inhibitor WP1066 affects human tongue squamous cell carcinoma proliferation and apoptosis in vitro and in vivo].
OBJECTIVE To investigate the antitumour molecular mechanisms of WP1066 (STAT-3 inhibitor ) to human tongue squamous cell… 
2009
2009
Reduced Expression of an RNA-binding Protein by Prolactin Leads to Translational Silencing of Programmed Cell Death Protein 4 and Apoptosis in Newt Spermatogonia
Recent studies indicate that the balance between cell survival and proapoptotic signals determines which cells commit to life or… 
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