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PAXIP1 gene

Known as: PAX TRANSACTIVATION DOMAIN-INTERACTING PROTEIN, CAGF28, PAXIP1 
This gene is involved in the regulation of both histone methylation and gene expression.
National Institutes of Health

Related topics

Related topics

4 relations
DNA RepairPAXIP1 protein, humanProtein methylationTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
An OB-fold complex controls the repair pathways for DNA double-strand breaks
53BP1 with its downstream proteins, RIF1, PTIP and REV7, antagonizes BRCA1-dependent homologous recombination (HR) and promotes… 
Highly Cited
2014
Highly Cited
2014
PTIP associates with Artemis to dictate DNA repair pathway choice
PARP inhibitors (PARPi) are being used in patients with BRCA1/2 mutations; however, doubly deficient BRCA1−/−53BP1−/− tumors… 
2013
2013
The evolution and function of the Pax/Six regulatory network in sponges
Examining the origins of highly conserved gene regulatory networks (GRNs) will inform our understanding of the evolution of… 
2013
2013
DNA repair pathway choice—a PTIP of the hat to 53BP1
DNA double‐stranded breaks (DSBs) are highly cytotoxic lesions that can induce genome rearrangements if not accurately repaired… 
Highly Cited
2011
Highly Cited
2011
Role of PTIP in Class Switch Recombination and Long-Range Chromatin Interactions at the Immunoglobulin Heavy Chain Locus
ABSTRACT How distal transcriptional enhancer sequences interact with proximal promoters is poorly understood within the context… 
2010
2010
PTIP promotes DNA double‐strand break repair through homologous recombination
PTIP (Pax2 transactivation domain‐interacting protein) is a large nuclear protein containing six BRCT (BRCA1 C‐Terminal) domains… 
Highly Cited
2005
Highly Cited
2005
Pax6-dependence of Six3, Eya1 and Dach1 expression during lens and nasal placode induction.
Highly Cited
2004
Highly Cited
2004
Human PTIP Facilitates ATM-mediated Activation of p53 and Promotes Cellular Resistance to Ionizing Radiation*
Mus musculusPax2 transactivation domain-interacting protein (Ptip) is an essential gene required for the maintenance of genome… 
Highly Cited
1999
Highly Cited
1999
Piracy in the Graeco-Roman world
1. Introduction 2. The origins of piracy from the Bronze Age to Alexander 3. Hellenistic piracy 4. Cilician piracy 5. Pompey and… 
Highly Cited
1996
Highly Cited
1996
Mutations in zebrafish genes affecting the formation of the boundary between midbrain and hindbrain.
Mutations in two genes affect the formation of the boundary between midbrain and hindbrain (MHB): no isthmus (noi) and… 
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