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Mutations affecting segment number and polarity in Drosophila
The phenotypes of the mutant embryos indicate that the process of segmentation involves at least three levels of spatial organization: the entire egg as developmental unit, a repeat unit with the length of two segments, and the individual segment.
The zebrafish reference genome sequence and its relationship to the human genome
A high-quality sequence assembly of the zebrafish genome is generated, made up of an overlapping set of completely sequenced large-insert clones that were ordered and oriented using a high-resolution high-density meiotic map, providing a clearer understanding of key genomic features such as a unique repeat content, a scarcity of pseudogenes, an enrichment of zebra fish-specific genes on chromosome 4 and chromosomal regions that influence sex determination.
Zebrafish : a practical approach
This book impressively describes how to combine classical genetic analysis in this organism with techniques for molecular analysis of gene function and experimental manipulation of embryos, in a way that is sure to inspire an expanding community of scientists to exploit the zebrafish system in their research.
Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva.
Analysis of the behavioral defects suggests that these genes participate in the diverse locomotion patterns observed, such as touch response, rhythmic tail movements, equilibrium control, or that they simply confer general motility to the animal.
The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo.
The organization of the anterior pattern in the Drosophila embryo is mediated by the maternal effect gene bicoid and the mRNA is localized at the anterior tip of oocyte and early embryo until the cellular blastoderm stage.
Control of her1 expression during zebrafish somitogenesis by a delta-dependent oscillator and an independent wave-front activity.
It is reported that the zebrafish gene after eight (aei) that is required for both somitogenesis and neurogenesis encodes the Notch ligand DeltaD, and analysis indicates that the smooth sequence of formation, refinement, and fading of her1 stripes in the PSM is governed by two separate activities.
Genes establishing dorsoventral pattern formation in the zebrafish embryo: the ventral specifying genes.
The similar and overlapping phenotypes of mutants of the 6 genes identified suggest that they function in a common pathway, which begins in oogenesis, but also depends on factors provided after the onset of zygotic transcription, presumably during blastula stages.