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PANX1 gene

Known as: PX1, UNQ2529, PANX1 
National Institutes of Health

Related topics

Related topics

1 relation
innexin activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Liver X receptor β activation induces pyroptosis of human and murine colon cancer cells
Liver X receptors (LXRs) have been proposed to have some anticancer properties, through molecular mechanisms that remain elusive… 
Review
2014
Review
2014
ATP Signaling in Brain: Release, Excitotoxicity and Potential Therapeutic Targets
Adenosine 5′-triphosphate (ATP) is released as a genuine co-transmitter, or as a principal purinergic neurotransmitter, in an… 
Review
2013
Review
2013
Autophagy-dependent ATP release from dying cells via lysosomal exocytosis
ATP not only represents a key molecule for the intracellular storage and utilization of energy, but also plays a central role in… 
Highly Cited
2010
Highly Cited
2010
Pannexin 1 is the conduit for low oxygen tension-induced ATP release from human erythrocytes.
Erythrocytes release ATP in response to exposure to the physiological stimulus of lowered oxygen (O(2)) tension as well as… 
Highly Cited
2009
Highly Cited
2009
Pannexin 1 contributes to ATP release in airway epithelia.
ATP is a paracrine regulator of critical airway epithelial cell functions, but the mechanism of its release is poorly understood… 
Highly Cited
2008
Highly Cited
2008
Maxi-anion channel as a candidate pathway for osmosensitive ATP release from mouse astrocytes in primary culture
In the present study, we aimed to evaluate the pathways contributing to ATP release from mouse astrocytes during hypoosmotic… 
Highly Cited
2007
Highly Cited
2007
Tumor-suppressive effects of pannexin 1 in C6 glioma cells.
Mammalian gap junction proteins, connexins, have long been implicated in tumor suppression. Recently, a novel family of proteins… 
Highly Cited
2007
Highly Cited
2007
An Innexin-Dependent Cell Network Establishes Left-Right Neuronal Asymmetry in C. elegans
Highly Cited
2005
Highly Cited
2005
Characterization of innexin gene expression and functional roles of gap-junctional communication in planarian regeneration.
Review
1999
Review
1999
Genetic diseases and gene knockouts reveal diverse connexin functions.
Intercellular channels present in gap junctions allow cells to share small molecules and thus coordinate a wide range of… 
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