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PAK2 kinase

Known as: gamma PAK, p21-Activated Kinase 2, PAK-2 Kinase 
National Institutes of Health

Related topics

Related topics

3 relations
PAK2 geneRibosomal Protein S6 Kinase

Broader (1)

p21-Activated Kinases

Papers overview

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2019
2019
The novel immunosuppressant prenylated quinolinecarboxylic acid-18 (PQA-18) suppresses macrophage differentiation and cytotoxicity in xenotransplantation.
2015
2015
Pak2 Links TCR Signaling Strength to the Development of Regulatory T Cells and Maintains Peripheral Tolerance
Although significant effort has been devoted to understanding the thymic development of Foxp3+ regulatory T cells (Tregs), the… 
Highly Cited
2011
Highly Cited
2011
Proteome analysis of erythrocytes lacking AMP-activated protein kinase reveals a role of PAK2 kinase in eryptosis.
Activation of AMP-activated protein kinase (AMPK) upon energy depletion stimulates energy production and limits energy… 
Highly Cited
2009
Highly Cited
2009
Dual Role of Cdc42 in Spindle Orientation Control of Adherent Cells
ABSTRACT The spindle orientation is regulated by the interaction of astral microtubules with the cell cortex. We have previously… 
2007
2007
Association of Nef with p21-Activated Kinase 2 Is Dispensable for Efficient Human Immunodeficiency Virus Type 1 Replication and Cytopathicity in Ex Vivo-Infected Human Lymphoid Tissue
ABSTRACT Interaction of the human immunodeficiency virus type 1 (HIV-1) Nef protein with p21-activated kinase 2 (PAK2) has been… 
2006
2006
Activation of p21-activated Kinase 2 and Its Association with Nef Are Conserved in Murine Cells but Are Not Sufficient to Induce an AIDS-like Disease in CD4C/HIV Transgenic Mice*
A well conserved feature of human immunodeficiency virus, type 1 (HIV-1) and simian immunodeficiency virus (SIV) Nef is the… 
2005
2005
Activation of p21-Activated Kinase 2 by Human Immunodeficiency Virus Type 1 Nef Induces Merlin Phosphorylation
ABSTRACT The accessory human immunodeficiency virus type 1 (HIV-1) protein Nef activates the autophosphorylation activity of p21… 
2003
2003
Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development.
The HIV-1 gene nef is important for progression toward AIDS and cellular depletion of the infected thymus. Expression of the Nef… 
2001
2001
Human immunodeficiency virus type 1 Nef selectively associates with a catalytically active subpopulation of p21-activated kinase 2 (PAK2) independently of PAK2 binding to Nck or beta-PIX.
We have recently identified the Nef-associated serine-threonine kinase (NAK) as the p21-activated kinase 2 (PAK2). Here we have… 
Review
1998
Review
1998
Caspase-mediated activation of PAK2 during apoptosis: proteolytic kinase activation as a general mechanism of apoptotic signal transduction?
p21-activated kinase 2 (PAK2) is proteolytically cleaved during apoptosis through the action of DEVD-sensitive caspase(s). This… 
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