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PAK2 gene

Known as: PAK65, p21 protein (Cdc42/Rac)-activated kinase 2, p21 PROTEIN-ACTIVATED KINASE 2 
National Institutes of Health

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Related topics

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PAK1 genePAK2 kinase

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Ribosomal Protein S6 Kinase

Papers overview

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Highly Cited
2008
Highly Cited
2008
Pak1 and Pak2 Mediate Tumor Cell Invasion through Distinct Signaling Mechanisms
ABSTRACT Pak kinases are thought to play critical roles in cell migration and invasion. Here, we analyze the roles of Pak1 and… 
Highly Cited
2007
Highly Cited
2007
Apoptotic signaling in methylglyoxal‐treated human osteoblasts involves oxidative stress, c‐Jun N‐terminal kinase, caspase‐3, and p21‐activated kinase 2
Methylglyoxal (MG) is a reactive dicarbonyl compound endogenously produced mainly from glycolytic intermediates. MG is cytotoxic… 
2005
2005
Regulation of the Interaction of Pak2 with Cdc42 via Autophosphorylation of Serine 141*
Pak2, a member of the p21-activated protein kinase (Pak) family, is activated in response to a variety of stresses and is… 
Highly Cited
2002
Highly Cited
2002
Phosphorylation of p85 βPIX, a Rac/Cdc42-specific Guanine Nucleotide Exchange Factor, via the Ras/ERK/PAK2 Pathway Is Required for Basic Fibroblast Growth Factor-induced Neurite Outgrowth*
Guanine nucleotide exchange factors (GEFs) have been implicated in growth factor-induced neuronal differentiation through the… 
Highly Cited
2000
Highly Cited
2000
Phosphorylation of Myosin Light Chain Kinase by p21-activated Kinase PAK2*
Phosphorylation of myosin II regulatory light chains (RLC) by Ca2+/calmodulin-dependent myosin light chain kinase (MLCK) is a… 
Highly Cited
2000
Highly Cited
2000
Lentivirus Nef Specifically Activates Pak2
ABSTRACT Nef proteins from human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) have been found to… 
Highly Cited
2000
Highly Cited
2000
Apoptotic signalling cascade in photosensitized human epidermal carcinoma A431 cells: involvement of singlet oxygen, c-Jun N-terminal kinase, caspase-3 and p21-activated kinase 2.
Photodynamic treatment (PDT) elicits diverse cellular responses and can also cause apoptosis. In the present study the cascade of… 
2000
2000
Regulation of Xenopus p21-activated Kinase (X-PAK2) by Cdc42 and Maturation-promoting Factor Controls Xenopus Oocyte Maturation*
Signal transduction cascades involved in regulation of the cell cycle machinery are poorly understood. In theXenopus oocyte model… 
Highly Cited
2000
Highly Cited
2000
Up-regulation of p21- and RhoA-activated protein kinases in human pregnant myometrium.
The role of small ras homologous GTP-binding proteins in the regulation of smooth muscle contractility has become increasingly… 
Highly Cited
1999
Highly Cited
1999
Identification of the Nef-associated kinase as p21-activated kinase 2
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