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Serum Autoantibody Signature of Ductal Carcinoma In Situ Progression to Invasive Breast Cancer
Purpose: The identification of markers associated with progression to invasive breast cancer (IBC) is a major factor that can guide physicians in the initial therapeutic decision and the managementExpand
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Pemphigus vulgaris antigen mRNA quantification for the staging of sentinel lymph nodes in head and neck cancer
Background:Molecular diagnosis has been proposed to enhance the intra-operative diagnosis of sentinel lymph node (SLN) invasion in head and neck squamous cell carcinoma (HNSCC). Although cytokeratinExpand
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Identification and validation of new autoantibodies for the diagnosis of DCIS and node negative early‐stage breast cancers
Evidence of circulating autoantibodies in cancer patient sera has created opportunities for exploiting them as biomarkers. We report the identification and the clinical validation of an autoantibodyExpand
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Use of Autoantibodies to Detect the Onset of Breast Cancer
The widespread use of screening mammography has resulted in increased detection of early-stage breast disease, particularly for in situ carcinoma and early-stage breast cancer. However, the majorityExpand
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Concurrent or sequential letrozole with adjuvant breast radiotherapy: final results of the CO-HO-RT phase II randomized trial.
BACKGROUND We present here final clinical results of the COHORT trial and both translational sub-studies aiming at identifying patients at risk of radiation-induced subcutaneous fibrosis (RISF): (i)Expand
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Candidate gene biodosimetry markers of exposure to external ionizing radiation in human blood: A systematic review
Purpose To compile a list of genes that have been reported to be affected by external ionizing radiation (IR) and to assess their performance as candidate biomarkers for individual human radiationExpand
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A Multiparametric Serum Marker Panel as a Complementary Test to Mammography for the Diagnosis of Node-Negative Early-Stage Breast Cancer and DCIS in Young Women
Background: The sensitivity of mammography for the detection of small lesions, including node-negative early-stage (T1N0) primary breast cancer (PBC) and ductal carcinoma in situ (DCIS), isExpand
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Analysis of Saliva Gene Expression during Head and Neck Cancer Radiotherapy: A Pilot Study
Saliva, a biological fluid, is a promising candidate for novel approaches to prognosis, clinical diagnosis, monitoring and management of patients with both oral and systemic diseases. However, toExpand
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Quantitative proteomic analysis reveals AK2 as potential biomarker for late normal tissue radiotoxicity
BackgroundBiomarkers for predicting late normal tissue toxicity to radiotherapy are necessary to personalize treatments and to optimize clinical benefit. Many radiogenomic studies have been publishedExpand
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Proteomic approaches to identify biomarkers predictive of radiotherapy outcomes
To be highly successful, a radiotherapeutic dose must be sufficiently large to destroy radioresistant tumors, yet avoid injuring the surrounding healthy tissue. However, many patients exhibit highExpand
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