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Organoids
Known as:
Organoid
An organization of cells into an organ-like structure. Organoids can be generated in culture. They are also found in certain neoplasms.
National Institutes of Health
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Related topics
7 relations
Blood supply aspects
Glyoxysomes
Microbiological
Process of secretion
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Cell Stress in Cortical Organoids Impairs Molecular Subtype Specification
A. Bhaduri
,
Madeline G. Andrews
,
+10 authors
A. Kriegstein
Nature
2019
Corpus ID: 210951229
Cortical organoids are self-organizing three-dimensional cultures that model features of the developing human cerebral cortex 1…
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Highly Cited
2019
Highly Cited
2019
Human blood vessel organoids as a model of diabetic vasculopathy
Reiner A. Wimmer
,
Alexandra Leopoldi
,
+17 authors
J. Penninger
Nature
2019
Corpus ID: 58014320
The increasing prevalence of diabetes has resulted in a global epidemic1. Diabetes is a major cause of blindness, kidney failure…
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Highly Cited
2018
Highly Cited
2018
An in vivo model of functional and vascularized human brain organoids
A. Mansour
,
J. T. Gonçalves
,
+8 authors
F. Gage
Nature Biotechnology
2018
Corpus ID: 4898061
Differentiation of human pluripotent stem cells to small brain-like structures known as brain organoids offers an unprecedented…
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Highly Cited
2018
Highly Cited
2018
Flow-enhanced vascularization and maturation of kidney organoids in vitro
Kimberly A. Homan
,
Navin R Gupta
,
+9 authors
Ryuji Morizane
Nature Methods
2018
Corpus ID: 59944967
Kidney organoids derived from human pluripotent stem cells have glomerular- and tubular-like compartments that are largely…
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Highly Cited
2018
Highly Cited
2018
Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer.
H. Tiriac
,
P. Belleau
,
+67 authors
D. Tuveson
Cancer Discovery
2018
Corpus ID: 46918234
Pancreatic cancer is the most lethal common solid malignancy. Systemic therapies are often ineffective, and predictive biomarkers…
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Highly Cited
2018
Highly Cited
2018
Generation of human vascularized brain organoids
Missy T. Pham
,
K. Pollock
,
+5 authors
B. Waldau
NeuroReport
2018
Corpus ID: 4826147
The aim of this study was to vascularize brain organoids with a patient’s own endothelial cells (ECs). Induced pluripotent stem…
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Highly Cited
2015
Highly Cited
2015
Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver
Meritxell Huch
,
H. Gehart
,
+20 authors
H. Clevers
Cell
2015
Corpus ID: 6761624
Highly Cited
2015
Highly Cited
2015
Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids
Benjamin S. Freedman
,
Craig R. Brooks
,
+18 authors
J. Bonventre
Nature Communications
2015
Corpus ID: 13141409
Human-pluripotent-stem-cell-derived kidney cells (hPSC-KCs) have important potential for disease modelling and regeneration…
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Highly Cited
2014
Highly Cited
2014
Organoid Cultures Derived from Patients with Advanced Prostate Cancer
D. Gao
,
I. Vela
,
+36 authors
Yu Chen
Cell
2014
Corpus ID: 17819649
Highly Cited
2011
Highly Cited
2011
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
Toshiro Sato
,
J. V. Es
,
+7 authors
H. Clevers
Nature
2011
Corpus ID: 4311453
Homeostasis of self-renewing small intestinal crypts results from neutral competition between Lgr5 stem cells, which are small…
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