Organoids

Known as: Organoid 
An organization of cells into an organ-like structure. Organoids can be generated in culture. They are also found in certain neoplasms.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1946-2017
020040060019462016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Since the emergence of Zika virus (ZIKV), reports of microcephaly have increased considerably in Brazil; however, causality… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2015
Highly Cited
2015
Pancreatic cancer is one of the most lethal malignancies due to its late diagnosis and limited response to treatment. Tractable… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2015
Highly Cited
2015
In Rspondin-based 3D cultures, Lgr5 stem cells from multiple organs form ever-expanding epithelial organoids that retain their… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2014
Highly Cited
2014
The lack of in vitro prostate cancer models that recapitulate the diversity of human prostate cancer has hampered progress in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2014
Highly Cited
2014
Human brain development exhibits several unique aspects, such as increased complexity and expansion of neuronal output, that have… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Single murine and human intestinal stem cells can be expanded in culture over long time periods as genetically and phenotypically… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2013
Highly Cited
2013
We recently established conditions allowing for long-term expansion of epithelial organoids from intestine, recapitulating… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
BACKGROUND & AIMS We previously established long-term culture conditions under which single crypts or stem cells derived from… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Homeostasis of self-renewing small intestinal crypts results from neutral competition between Lgr5 stem cells, which are small… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2009
Highly Cited
2009
The intestinal epithelium is the most rapidly self-renewing tissue in adult mammals. We have recently demonstrated the presence… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
Is this relevant?