Ondansetron

Known as: 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-, Ondansetron [Chemical/Ingredient], Ondansetron, (+,-)-Isomer 
A carbazole derivative with antiemetic activity. As a selective serotonin receptor antagonist, ondansetron competitively blocks the action of… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
BACKGROUND This pivotal phase III trial evaluated the efficacy and safety of palonosetron in preventing acute and delayed… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND We compared an aprepitant regimen with a control regimen of ondansetron + dexamethasone given for 4 days. PATIENTS… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Vomiting limits the success of oral rehydration in children with gastroenteritis. We conducted a double-blind trial to… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND At dosages above 0.1 mg/kg, droperidol induces a dose-dependent QTc interval prolongation. Although subject to… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Untreated, one third of patients who undergo surgery will have postoperative nausea and vomiting. Although many trials… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE Ondansetron (Zofran) is a drug used for the treatment of nausea and vomiting caused by cancer chemotherapy. Despite the… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Although all first-generation 5-HT(3) receptor antagonists demonstrate efficacy in preventing acute chemotherapy… (More)
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Highly Cited
2000
Highly Cited
2000
CONTEXT Early-onset alcoholism differs from late-onset alcoholism by its association with greater serotonergic abnormality and… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND In an era of growing economic constraints on healthcare delivery, anesthesiologists are increasingly expected to… (More)
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Highly Cited
1998
Highly Cited
1998
UNLABELLED Although ondansetron (4 mg I.V.) is effective in the prevention and treatment of postoperative nausea and vomiting… (More)
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