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Ondansetron

Known as: 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-, Ondansetron [Chemical/Ingredient], Ondansetron, (+,-)-Isomer 
A carbazole derivative with antiemetic activity. As a selective serotonin receptor antagonist, ondansetron competitively blocks the action of… 
National Institutes of Health

Related topics

Related topics

38 relations
2 ML Ondansetron 2 MG/ML InjectionAlcoholic Intoxication, ChronicCYP1A2 protein, humanCytochrome P450 2D6, human

Narrower (5)

8-hydroxyondansetronGR38032FOndansetron HydrochlorideSN-307

Broader (8)

Anti-Anxiety AgentsAntiemeticsAntipruriticsAntipsychotic Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Serotonergic receptor mechanisms underlying antidepressant-like action in the progesterone withdrawal model of hormonally induced depression in rats
Highly Cited
2012
Highly Cited
2012
An increase in spinal cord noradrenaline is a major contributor to the antihyperalgesic effect of antidepressants after peripheral nerve injury in the rat
Highly Cited
2005
Highly Cited
2005
Improved p50 auditory gating with ondansetron in medicated schizophrenia patients.
OBJECTIVE Most schizophrenia patients have a deficit in auditory sensory gating, which appears to be mediated by the alpha-7… 
Highly Cited
2004
Highly Cited
2004
Descending serotonergic facilitation mediated through rat spinal 5HT3 receptors is unaltered following carrageenan inflammation
Highly Cited
2003
Highly Cited
2003
A Comparison of Dexamethasone, Ondansetron, and Dexamethasone plus Ondansetron as Prophylactic Antiemetic and Antipruritic Therapy in Patients Receiving Intrathecal Morphine for Major Orthopedic…
In a prospective, double-blinded, randomized trial, we evaluated the efficacy of IV (a) dexamethasone 8 mg, (b) ondansetron 8 mg… 
Highly Cited
2001
Highly Cited
2001
Acupuncture versus ondansetron in the prevention of postoperative vomiting: A study of children undergoing dental surgery
This study compares the anti-emetic effect of acupuncture with that of ondansetron and a placebo. Ninety children undergoing… 
Highly Cited
2000
Highly Cited
2000
Prophylactic Intravenous Ondansetron Reduces the Incidence of Intrathecal Morphine-Induced Pruritus in Patients Undergoing Cesarean Delivery
Pruritus is a common side effect of intrathecal morphine injection for postoperative pain control. Its incidence is especially… 
Highly Cited
1998
Highly Cited
1998
Docetaxel (Taxotere) plus cisplatin: an active and well-tolerated combination in patients with advanced non-small cell lung cancer.
Highly Cited
1996
Highly Cited
1996
Involvement of GABA systems in acetylcholine release induced by 5-HT3 receptor blockade in slices from rat entorhinal cortex
Review
1995
Review
1995
Ventral tegmental area 5-HT receptors: mesolimbic dopamine release and behavioural studies
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