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GR38032F

Known as: GR 38032F, GR-38032F 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
The newly recognized class of 5-hydroxytryptamine receptors (5HT3) may be involved in the induction of nausea, since their… Expand
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Highly Cited
1991
Highly Cited
1991
Recent data have supported a role for serotonin (5-HT) in the self-administration of cocaine by laboratory rats. More… Expand
Highly Cited
1989
Highly Cited
1989
1 The purpose of the present study was to identify and investigate the role of 5‐hydroxytryptamine3 (5‐HT3) receptors in the area… Expand
Highly Cited
1988
Highly Cited
1988
1 This paper describes the pharmacology of the novel 5‐hydroxytryptamine3 (5‐HT3) receptor antagonist GR38032F. 2 On the isolated… Expand
Highly Cited
1988
Highly Cited
1988
1 The highly selective 5‐HT3‐receptor antagonist, GR38032F, has been tested in five animal models predictive for anxiolytic… Expand
Highly Cited
1988
Highly Cited
1988
GR-C507/75 (GR38032F) antagonizes the 5-HT3 (serotonin) receptor and prevents cisplatin-induced emesis in animals. In this dose… Expand
Highly Cited
1987
Highly Cited
1987
1 The ability of the selective 5‐HT3 receptor antagonist GR38032F to reduce raised mesolimbic dopaminergic activity was studied… Expand
Highly Cited
1987
Highly Cited
1987
Functional serotonin (5-hydroxytryptamine, 5-HT) receptors have been divided into three subtypes: 5-HT1,-like, 5-HT2 and 5-HT3… Expand
Highly Cited
1987
Highly Cited
1987
15 patients receiving cytotoxic drugs (other than cisplatin) that had previously produced nausea and vomiting refractory to first… Expand
Highly Cited
1987
Highly Cited
1987
GR38032F is a highly selective 5HT3-receptor antagonist which inhibits vomiting induced by cisplatin, cyclophosphamide or X… Expand