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The newly recognized class of 5-hydroxytryptamine receptors (5HT3) may be involved in the induction of nausea, since their… Expand Recent data have supported a role for serotonin (5-HT) in the self-administration of cocaine by laboratory rats. More… Expand 1 The purpose of the present study was to identify and investigate the role of 5‐hydroxytryptamine3 (5‐HT3) receptors in the area… Expand 1 This paper describes the pharmacology of the novel 5‐hydroxytryptamine3 (5‐HT3) receptor antagonist GR38032F. 2 On the isolated… Expand 1 The highly selective 5‐HT3‐receptor antagonist, GR38032F, has been tested in five animal models predictive for anxiolytic… Expand GR-C507/75 (GR38032F) antagonizes the 5-HT3 (serotonin) receptor and prevents cisplatin-induced emesis in animals. In this dose… Expand 1 The ability of the selective 5‐HT3 receptor antagonist GR38032F to reduce raised mesolimbic dopaminergic activity was studied… Expand Functional serotonin (5-hydroxytryptamine, 5-HT) receptors have been divided into three subtypes: 5-HT1,-like, 5-HT2 and 5-HT3… Expand 15 patients receiving cytotoxic drugs (other than cisplatin) that had previously produced nausea and vomiting refractory to first… Expand GR38032F is a highly selective 5HT3-receptor antagonist which inhibits vomiting induced by cisplatin, cyclophosphamide or X… Expand