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Oncogene YES-1
Known as:
YES1
, YES1 Gene
The gene product of oncogene YES-1 is associated with tyrosine kinase activity and its amino acid sequence shows high similarity with that of SRC…
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National Institutes of Health
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Related topics
Related topics
7 relations
18p11.31-p11.21
Homo sapiens
Neoplastic Cell Transformation
Protein phosphorylation
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Circ_Lrp6, a Circular RNA Enriched in Vascular Smooth Muscle Cells, Acts as a Sponge Regulating miRNA-145 Function
I. F. Hall
,
Montserrat Climent
,
+8 authors
L. Elia
Circulation Research
2019
Corpus ID: 58667912
Rationale: microRNAs (miRNAs) modulate gene expression by repressing translation of targeted genes. Previous work has established…
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2019
2019
YES1 Drives Lung Cancer Growth and Progression and Predicts Sensitivity to Dasatinib.
I. Garmendia
,
M. Pajares
,
+25 authors
J. Agorreta
American Journal of Respiratory and Critical Care…
2019
Corpus ID: 174810894
RATIONALE the characterization of new genetic alterations is essential to assign effective personalized therapies in non-small…
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2017
2017
Yes1 signaling mediates the resistance to Trastuzumab/Lap atinib in breast cancer
Tatsuaki Takeda
,
H. Yamamoto
,
+17 authors
S. Toyooka
PLoS ONE
2017
Corpus ID: 52869801
Background Overexpression of human epidermal growth factor receptor 2 (HER2) is observed in approximately 15–23% of breast…
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Highly Cited
2016
Highly Cited
2016
Long noncoding RNA H19 competitively binds miR‐17‐5p to regulate YES1 expression in thyroid cancer
Lin Liu
,
Jian Yang
,
Xuchao Zhu
,
Dan Li
,
Zhongwei Lv
,
Xiaoping Zhang
The FEBS Journal
2016
Corpus ID: 34407660
The long noncoding RNA H19 is overexpressed in many cancers and acts as an oncogene. Here, we investigated the role of H19 in…
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2015
2015
MiR‐17–5p Up‐Regulates YES1 to Modulate the Cell Cycle Progression and Apoptosis in Ovarian Cancer Cell Lines
Lan Li
,
Li He
,
+4 authors
Hua Tang
Journal of Cellular Biochemistry
2015
Corpus ID: 19721766
MicroRNAs (miRNAs) are small, non‐coding RNAs that participate in the regulation of gene expression. Although many studies have…
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Highly Cited
2014
Highly Cited
2014
The Inhibition of Src Family Kinase Suppresses Pancreatic Cancer Cell Proliferation, Migration, and Invasion
Dong Wook Je
,
Young Moon O
,
Y. Ji
,
Yunkyung Cho
,
Dong Hyeon Lee
Pancreas
2014
Corpus ID: 26142067
Objectives Src is considered a rising therapeutic target for the treatment of solid tumors, and Src family kinases (SFKs…
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2010
2010
Identification of the YES1 Kinase as a Therapeutic Target in Basal-Like Breast Cancers.
E. Bilal
,
G. Alexe
,
+6 authors
G. Bhanot
Genes & cancer
2010
Corpus ID: 25630191
Normal cellular behavior can be described as a complex, regulated network of interaction between genes and proteins. Targeted…
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Highly Cited
2008
Highly Cited
2008
Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.
E. Polverini
,
G. Rangaraj
,
D. Libich
,
J. Boggs
,
G. Harauz
Biochemistry
2008
Corpus ID: 14641165
Myelin basic protein (MBP) is a multifunctional protein involved in maintaining the stability and integrity of the myelin sheath…
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2002
2002
Novel targets for the 18p11.3 amplification frequently observed in esophageal squamous cell carcinomas.
K. Nakakuki
,
I. Imoto
,
+5 authors
J. Inazawa
Carcinogenesis
2002
Corpus ID: 46684287
Amplification of DNA in certain chromosomal regions, with consequent over-expression of specific genes within these amplicons…
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Highly Cited
2001
Highly Cited
2001
Pharmacogenomic dissection of resistance to thymidylate synthase inhibitors.
W. Wang
,
S. Marsh
,
J. Cassidy
,
H. Mcleod
Cancer Research
2001
Corpus ID: 9645162
Chemoresistance is a major obstacle for successful cancer treatment. Gene amplification and altered expression are the main…
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