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Oncogene YES-1

Known as: YES1, YES1 Gene 
The gene product of oncogene YES-1 is associated with tyrosine kinase activity and its amino acid sequence shows high similarity with that of SRC… Expand
National Institutes of Health

Related topics

Related topics

7 relations
18p11.31-p11.21Homo sapiensNeoplastic Cell TransformationProtein phosphorylation
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Papers overview

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Highly Cited
2016
Highly Cited
2016
Long noncoding RNA H19 competitively binds miR-17-5p to regulate YES1 expression in thyroid cancer.
The long noncoding RNA H19 is overexpressed in many cancers and acts as an oncogene. Here, we investigated the role of H19 in… Expand
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2015
2015
Use of mechanistic models to integrate and analyze multiple proteomic datasets.
Proteins in cell signaling networks tend to interact promiscuously through low-affinity interactions. Consequently, evaluating… Expand
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2015
2015
Identification of miR-145 targets through an integrated omics analysis.
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression and protein synthesis. To characterize functions of… Expand
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2014
2014
The inhibition of SRC family kinase suppresses pancreatic cancer cell proliferation, migration, and invasion.
OBJECTIVES Src is considered a rising therapeutic target for the treatment of solid tumors, and Src family kinases (SFKs… Expand
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2013
2013
YES1 Activation Elicited by Heat Stress Is Anti-Apoptotic in Mouse Pachytene Spermatocytes1
ABSTRACT Deregulated expression of protein tyrosine phosphorylation has been implicated in testicular response to different… Expand
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2011
2011
Genomic imbalances in esophageal carcinoma cell lines involve Wnt pathway genes.
AIM To identify molecular markers shared across South African esophageal squamous cell carcinoma (ESCC) cell lines using… Expand
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2008
2008
Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.
Myelin basic protein (MBP) is a multifunctional protein involved in maintaining the stability and integrity of the myelin sheath… Expand
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2002
2002
Novel targets for the 18p11.3 amplification frequently observed in esophageal squamous cell carcinomas.
Amplification of DNA in certain chromosomal regions, with consequent over-expression of specific genes within these amplicons… Expand
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2001
2001
Pharmacogenomic dissection of resistance to thymidylate synthase inhibitors.
Chemoresistance is a major obstacle for successful cancer treatment. Gene amplification and altered expression are the main… Expand
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1993
1993
STS map of genes and anonymous DNA fragments on human chromosome 18 using a panel of somatic cell hybrids.
Somatic cell hybrids containing different deleted regions of chromosome 18 derived from patients with balanced translocations or… Expand
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