OTX2 gene

Known as: orthodenticle homeobox 2, Orthodenticle Homeobox 2 Gene, OTX2 
This gene is involved in both embryonic development and transcriptional regulation.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Specific transfer of (orthodenticle homeobox 2) Otx2 homeoprotein into GABAergic interneurons expressing parvalbumin (PV) is… (More)
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Highly Cited
2005
Highly Cited
2005
Major malformations of the human eye, including microphthalmia and anophthalmia, are examples of phenotypes that recur in… (More)
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Highly Cited
2005
Highly Cited
2005
The transcription factor Otx2 is required to determine mesencephalic versus metencephalic (cerebellum/pons) territory during… (More)
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Highly Cited
2004
Highly Cited
2004
The specification of distinct neuronal cell-types is controlled by inducing signals whose interpretation in distinct areas along… (More)
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Highly Cited
2001
Highly Cited
2001
Otx2 and Gbx2 are among the earliest genes expressed in the neuroectoderm, dividing it into anterior and posterior domains with a… (More)
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Highly Cited
2000
Highly Cited
2000
Otx2 is expressed in the mesencephalon and prosencephalon, and Gbx2 is expressed in the rhombencephalon around stage 10. Loss-of… (More)
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Highly Cited
1998
Highly Cited
1998
The homeobox gene Otx2 is a mouse cognate of the Drosophila orthodenticle gene, which is required for development of the brain… (More)
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Highly Cited
1997
Highly Cited
1997
The homeobox gene otx2 is a key regulator of positional identity in vertebrates, however its downstream target genes and… (More)
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Highly Cited
1996
Highly Cited
1996
Mouse Otx2 is a bicoid-class homeobox gene, related to the Drosophila orthodenticle (otd) gene. Expression of this gene is… (More)
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Highly Cited
1992
Highly Cited
1992
INSIGHT into the genetic control of the identity of specific regions along the body axis of vertebrates1 has resulted primarily… (More)
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