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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
The National Institutes of Health Mammalian Gene Collection (MGC) Program is a multiinstitutional effort to identify and sequence a cDNA clone containing a complete ORF for each human and mouse gene.Expand
Genome Sequence of Aedes aegypti, a Major Arbovirus Vector
An increase in genes encoding odorant binding, cytochrome P450, and cuticle domains relative to An. Expand
The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression.
An effort to share resources such that the maximum amount of gene-related data is obtained with the last redundancy is described, to have the data derived from the use of common reagents placed in public databases, and to create master arrays containing a representative cDNA clone from each gene. Expand
Normalization and subtraction: two approaches to facilitate gene discovery.
A subtractive hybridization approach designed specifically to eliminate (or reduce significantly the representation of) large pools of arrayed and (mostly) sequenced clones from normalized libraries yet to be (or just partly) surveyed is developed. Expand
Insights into a dinoflagellate genome through expressed sequence tag analysis
This is the most extensive collection to date of ESTs from a toxic dinoflagellate and will be instrumental to future research to understand the unique and complex cell biology of these organisms and for potentially identifying the genes involved in toxin production. Expand
The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene
The predicted functional properties of the pWD gene together with its strong homology to Mc1, genetic mapping data and identification of four independent disease–specific mutations, provide convincing evidence that pWD is the Wilson disease gene. Expand
Annotated expressed sequence tags and cDNA microarrays for studies of brain and behavior in the honey bee.
To accelerate the molecular analysis of behavior in the honey bee (Apis mellifera), expressed sequence tag (EST) and cDNA microarray resources for the bee brain are created and over 100 Apis transcript sequences conserved with other organisms appear to have been lost from the Drosophila genome. Expand
Transcriptional patterns in both host and bacterium underlie a daily rhythm of anatomical and metabolic change in a beneficial symbiosis
The transcriptional, metabolic, and ultrastructural characteristics of a diel rhythm that occurs in the symbiosis between the squid Euprymna scolopes and the luminous bacterium Vibrio fischeri are described. Expand
Molecular characterisation of aureocin A70, a multi-peptide bacteriocin isolated from Staphylococcus aureus.
Aureocin A70 is a multi-peptide non-lantibiotic bacteriocin, which is transported without processing, and four related peptides encoded by aurABCD operon are produced, expressed and excreted without post-translational modifications. Expand
Transcriptome analysis of the acoelomate human parasite Schistosoma mansoni
By analyzing automated Gene Ontology assignments, this work provides a detailed view of important S. mansoni biological systems, including characterization of metazoa-specific and eukarya-conserved genes, and identifies novel proteins to be investigated as vaccine candidates and potential drug targets. Expand