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Mouse Otx2 functions in the formation and patterning of rostral head.
The anterior part of the vertebrate head expresses a group of homeo box genes in segmentally restricted patterns during embryogenesis. Among these, Otx2 expression covers the entire fore- andExpand
Emx1 and Emx2 functions in development of dorsal telencephalon.
The genes Emx1 and Emx2 are mouse cognates of a Drosophila head gap gene, empty spiracles, and their expression patterns have suggested their involvement in regional patterning of the forebrain. ToExpand
Defects of urogenital development in mice lacking Emx2.
The homeobox gene Emx2 is a mouse homologue of a Drosophila head gap gene empty spiracles (ems) and is essential for the development of dorsal telencephalon (Yoshida, M., Suda, Y., Matsuo, I.,Expand
A novel transgenic technique that allows specific marking of the neural crest cell lineage in mice.
Neural crest cells are embryonic, multipotent stem cells that give rise to various cell/tissue types and thus serve as a good model system for the study of cell specification and mechanisms of cellExpand
Comparative transcriptome analysis reveals vertebrate phylotypic period during organogenesis
One of the central issues in evolutionary developmental biology is how we can formulate the relationships between evolutionary and developmental processes. Two major models have been proposed: theExpand
Evolution of the vertebral formulae in mammals: a perspective on developmental constraints.
Developmental constraints refer to biases that limit phenotypic changes during evolution. To examine the contribution of developmental constraints in the evolution of vertebrate morphology, weExpand
Identification and expression of the lamprey Pax6 gene: evolutionary origin of the segmented brain of vertebrates.
The Pax6 gene plays a developmental role in various metazoans as the master regulatory gene for eye patterning. Pax6 is also spatially regulated in particular regions of the neural tube. Because theExpand
The draft genomes of soft–shell turtle and green sea turtle yield insights into the development and evolution of the turtle–specific body plan
The unique anatomical features of turtles have raised unanswered questions about the origin of their unique body plan. We generated and analyzed draft genomes of the soft-shell turtle (PelodiscusExpand
Spatiotemporal expression patterns of chicken ovalbumin upstream promoter-transcription factors in the developing mouse central nervous system: evidence for a role in segmental patterning of the
Chicken ovalbumin upstream promoter-transcription factor (COUP-TF) genes encode transcription factors belonging to the orphan subfamily of the steroid/thyroid hormone receptor superfamily. TwoExpand
Heterotopic Shift of Epithelial-Mesenchymal Interactions in Vertebrate Jaw Evolution
Genes involved in late specification of the mandibular arch, the source of the vertebrate jaw, are expressed with similar patterns in the oral regions of chick and lamprey embryos. However,Expand