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OROTATE PHOSPHORIBOSYLTRANSFERASE

Known as: Phosphohydrolase, Orotidine-5'-Monophosphate, OMPase, orotidine 5' phosphoate pyrophosphorylase 
The enzyme catalyzing the formation of orotidine-5'-phosphoric acid (orotidylic acid) from orotic acid and 5-phosphoribosyl-1-pyrophosphate in the… 
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (2)

Hereditary orotic aciduria, type 1uridine 5'-monophosphate synthase
In BloodOrotate phosphoribosyltransferase:CCnc:Pt:Ser:QnProcess of secretionUMPS gene

Broader (1)

pentosyltransferase

Papers overview

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2006
2006
Population study of thymidylate synthase, dihydropyrimidine dehydrogenase and orotate phosphoribosyltransferase in patients with solid tumors
3639 Purpose: Thymidylate synthase(TS), dihydropyrimidine dehydrogenase(DPD) and orotate phosphoribosyltransferase(OPRT) has been… 
2004
2004
Gene expressions for thymidylate synthase (TS), orotate phosphoribosyltransferase (OPRT), and thymidine phosphorylase (TP), not dihydropyrimidine dehydrogenase (DPD), influence outcome of patients…
4050 Background: We have reported that patients with low TS, low DPD, high OPRT or low TP tumor showed a high response rate and a… 
1989
1989
Regulation of Salmonella typhimurium pyr gene expression: effect of changing both purine and pyrimidine nucleotide pools.
The synthesis of the pyrimidine biosynthetic enzymes is repressed by the pyrimidine nucleotide end-products of the pathway… 
1987
1987
Orotate phosphoribosyltransferase and hypoxanthine/guanine phosphoribosyltransferase from yeast: nuclear magnetic relaxation studies of the structures of enzyme-bound phosphoribosyl 1-pyrophosphate.
Nuclear magnetic relaxation rate measurements have been performed on the protons and phosphorus atoms of phosphoribosyl 1… 
1984
1984
Metabolic studies of high doses of allopurinol in humans.
In animals and in humans given high doses of allopurinol, the oxidation of allopurinol to oxipurinol is inhibited, resulting in a… 
1984
1984
Determination of a histidine residue at the yeast orotate phosphoribosyltransferase active-site.
A purified preparation of orotate phosphoribosyltransferase(0-PRTase) from yeast has been shown to catalyze the formation of… 
1980
1980
Dependence of the catalytic activities on the aggregation and conformation states of uridine 5'-phosphate synthase.
Uridine 5'-phosphate (UMP) synthase is a multifunctional protein that contains the last two enzyme activities for the de novo… 
1980
1980
Coordinate expression and developmental fate of pyrimidine biosynthetic enzymes in bacilius subtillus: Orotidine-5'-monophosphate pyrophosphorylase and orotidine-5'-monophosphate decarboxylase
1979
1979
Interconversion of different molecular weight forms of the orotate phosphoribosyltransferase.orotidine-5'-phosphate decarboxylase enzyme complex from mouse Ehrlich ascites cells.
Complex U consists of orotate phosphoribosyltransferase (EC 2.4.2.10) and orotidineG’-phosphate decarboxylase (EC 4.1.1.23), the… 
1979
1979
Divalent metal ion activation of the yeast orotate phosphoribosyltransferase catalyzed reaction.