OROTATE PHOSPHORIBOSYLTRANSFERASE

Known as: Phosphohydrolase, Orotidine-5'-Monophosphate, OMPase, orotidine 5' phosphoate pyrophosphorylase 
The enzyme catalyzing the formation of orotidine-5'-phosphoric acid (orotidylic acid) from orotic acid and 5-phosphoribosyl-1-pyrophosphate in the… (More)
National Institutes of Health

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2012
2012
Thymic carcinoma is a rare thymic epithelial tumor in which chemotherapy for advanced disease has not yet been established… (More)
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2012
2012
Tuberculosis (TB) is a chronic infectious disease caused mainly by Mycobacterium tuberculosis. The worldwide emergence of drug… (More)
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2007
2007
Orotate phosphoribosyltransferase (OPRTase, EC 2.4.2.10) catalyzes the Mg2+-dependent condensation of orotic acid (OA) with PRPP… (More)
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2004
2004
PURPOSE The anticancer agent 5-fluorouracil (5-FU) is clinically used against various cancers, including renal cell carcinoma… (More)
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1998
1998
It has been reported that the expression of thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD) and orotate… (More)
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1996
1996
Orotate phosphoribosyltransferase (OPRTase) catalyzes the magnesium-dependent conversion of alpha-D-phosphoribosylpyrophosphate… (More)
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1994
1994
Phosphoribosyltransferases (PRTases) are enzymes involved in the synthesis of purine, pyrimidine, and pyridine nucleotides. They… (More)
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Highly Cited
1993
Highly Cited
1993
The widely used and closely related Escherichia coli "wild types" W3110 and MG1655, as well as their common ancestor W1485… (More)
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1990
1990
The chemical mechanism of the phosphoribosyltransferases (PRTases), although largely unknown, may proceed either via a concerted… (More)
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1979
1979
Kinetic analysis of the reaction catalyzed by a homogeneous preparation of orotate phosphoribosyltransferase from yeast has… (More)
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