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OROTATE PHOSPHORIBOSYLTRANSFERASE

Known as: Phosphohydrolase, Orotidine-5'-Monophosphate, OMPase, orotidine 5' phosphoate pyrophosphorylase 
The enzyme catalyzing the formation of orotidine-5'-phosphoric acid (orotidylic acid) from orotic acid and 5-phosphoribosyl-1-pyrophosphate in the… 
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (2)

Hereditary orotic aciduria, type 1uridine 5'-monophosphate synthase
In BloodOrotate phosphoribosyltransferase:CCnc:Pt:Ser:QnProcess of secretionUMPS gene

Broader (1)

pentosyltransferase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1995
1995
Locations and functional roles of conserved lysine residues in Salmonella typhimurium orotate phosphoribosyltransferase.
Salmonella typhimurium orotate phosphoribosyltransferase (OPRTase) catalyzes the formation of orotidine 5'-monophosphate (OMP… 
1983
1983
Orotidylate-metabolizing enzymes of the human malarial parasite, Plasmodium falciparum, differ from host cell enzymes.
1983
1983
Cloning and physical analysis of the pyrF gene (coding for orotidine-5'-phosphate decarboxylase) from Escherichia coli K-12.
1983
1983
Structural gene coding for multifunctional protein carrying orotate phosphoribosyltransferase and OMP decarboxylase activity is located on long arm of human chromosome 3
In humans, deficiency in the last two enzymes of UMP biosynthesis, orotate phosphoribosyltransferase (OPRT) and OMP decarboxylase… 
Highly Cited
1982
Highly Cited
1982
UMP synthesis in the kinetoplastida.
Highly Cited
1982
Highly Cited
1982
Involvement of the glycosome of trypanosoma brucei in carbon dioxide fixation
Highly Cited
1980
Highly Cited
1980
Enzymology of human colon tumors.
1980
1980
Dynamics of modulation of biochemical programs in cancer cells.
Highly Cited
1979
Highly Cited
1979
Studies of the kinetic mechanism of orotate phosphoribosyltransferase from yeast.
Kinetic analysis of the reaction catalyzed by a homogeneous preparation of orotate phosphoribosyltransferase from yeast has… 
Highly Cited
1975
Highly Cited
1975
Studies on a pyrimidine phosphoribosyltransferase from murine leukemia P1534J. Partial purification, substrate specificity, and evidence for its existence as a bifunctional complex with orotidine 5…
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