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ORMDL3 gene

Known as: ORM1-LIKE PROTEIN 3, ORMDL sphingolipid biosynthesis regulator 3, ORMDL3 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
ORMDL3 but not neighboring 17q21 gene LRRC3C is expressed in human lungs and lung cells of asthmatics
CONFLIC TS OF INTERE S T Dr Till reports grants from ASIT Biotech and consultancy fees from Aimmune during the conduct of the… 
2020
2020
Treatment of Allergic Asthma with Fenretinide Formulation (LAU-7b) Downregulates ORMDL Sphingolipid Biosynthesis Regulator 3 (Ormdl3) Expression and Normalizes Ceramide Imbalance
Zona pellucida binding protein 2 (Zpbp2) and ORMDL sphingolipid biosynthesis regulator 3 (Ormdl3), mapped downstream of Zpbp2… 
2018
2018
Deep Resequencing of Ulcerative Colitis-Associated Genes Identifies Novel Variants in Candidate Genes in the Korean Population.
Background Genome-wide association studies and meta-analyses have revealed the genetic background of ulcerative colitis (UC) by… 
2017
2017
Association of ORMDL3 with rhinovirus‐induced endoplasmic reticulum stress and type I Interferon responses in human leucocytes
Children with risk alleles at the 17q21 genetic locus who wheeze during rhinovirus illnesses have a greatly increased likelihood… 
2017
2017
ORMDL3 may participate in the pathogenesis of bronchial epithelial‑mesenchymal transition in asthmatic mice with airway remodeling.
Asthma is a common chronic respiratory disease in children that is caused by a complex interaction between genetic and… 
2016
2016
Associations between NOD2, IRGM and ORMDL3 polymorphisms and pediatric-onset inflammatory bowel disease in the Lithuanian population.
2014
2014
The Genetics of Asthma: Towards a Personalised Approach to Diagnosis and Treatment
Nonbiased approaches, especially genome wide association studies (GWAS) have identified novel molecular targets in the… 
2013
2013
All-Trans Retinoic Acid Modulates ORMDL3 Expression via Transcriptional Regulation
All-trans retinoic acid (ATRA) is an active metabolite of Vitamin A, it shows protective effects on asthma, including maintains… 
2010
2010
Relationship between ORMDL3 Gene Polymorphism and Asthma in Children
Objective To explore the relationship between ORMDL3 gene polymorphism and Asthma in children.Methods 178 cases of children with… 
2008
2008
ORMDL3 – guilt by association?
A recent British–German study described ORMDL3 as a new asthma gene. Although the association with chromosome 17q12 marker is… 
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