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Nonsteroidal anti‐inflammatory drugs suppress cancer stem cells via inhibiting PTGS2 (cyclooxygenase 2) and NOTCH/HES1 and activating PPARG in colorectal cancer
NSAIDs could selectively reduce the colon CSCs and suppress 5‐FU‐induced increase of C SCs via inhibiting PTGS2 and NOTCH/HES1, and activating PPARG and decreased CBFRE and increased PPRE transcriptional activity and their relative protein expressions.
Colonoscopy as an adjunctive method for the diagnosis of irritable bowel syndrome: Focus on pain perception
Differences in pain perception during colonoscopy between IBS patients and non‐IBS patients are investigated and the sensitivity, specificity, and predictive values of pain scores are assessed to diagnose IBS.
Genetic polymorphisms of IL-23R and IL-17A and novel insights into their associations with inflammatory bowel disease
Insight is provided into the genetic and epigenetic interactions in the IL-23R/IL-17 axis that are associated with elevated expression of IL-17 and IBD pathogenesis and a significant inverse correlation between methylation extent of IVS1+17 and IL- 17A mRNA level.
Associations Between Genetic Variants in the IRGM Gene and Inflammatory Bowel Diseases in the Korean Population
This is the first study to identify SNP rs10065172 and rs72553867 in IRGM as principal CD susceptibility loci in an Asian population, and there was no significant association between the four SNPs and UC susceptibility.
Comparison of the Diagnostic Ability of Endoscopic Ultrasonography and Abdominopelvic Computed Tomography in the Diagnosis of Gastric Subepithelial Tumors
APCT showed a lower overall accuracy than EUS; however, APCT remains a useful modality for malignant/potentially malignant gastric SETs.
Prediction of Free Bowel Perforation in Patients with Intestinal Behçet’s Disease Using Clinical and Colonoscopic Findings
According to the results of this study, patients diagnosed with intestinal BD younger than 25 years, who had a history of prior laparotomy or volcano-shaped intestinal ulcers have an increased risk of free bowel perforation.
Risk Factors for Treatment Failure and Recurrence after Metronidazole Treatment for Clostridium difficile-associated Diarrhea.
The data suggest that diabetes mellitus and sepsis are independent risk factors for metronidazole treatment failure, and that operation history within 1 month of development of CDAD is a predictor of a recurrence after metronsidazoles treatment.