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Colonoscopy as an adjunctive method for the diagnosis of irritable bowel syndrome: Focus on pain perception
Background and Aim:  Visceral hypersensitivity is an important component of the pathophysiology of irritable bowel syndrome (IBS). In the present study, we investigated differences in pain perceptionExpand
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Genetic polymorphisms of IL-23R and IL-17A and novel insights into their associations with inflammatory bowel disease
Background and Aims To identify the associations of genetic and epigenetic variations in IL-23R and IL-17A with inflammatory bowel diseases (IBD). Methods The promoter and exon regions of IL-23R andExpand
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Nonsteroidal anti‐inflammatory drugs suppress cancer stem cells via inhibiting PTGS2 (cyclooxygenase 2) and NOTCH/HES1 and activating PPARG in colorectal cancer
Cancer stem cells (CSCs) play a pivotal role in cancer relapse or metastasis. We investigated the CSC‐suppressing effect of nonsteroidal anti‐inflammatory drugs (NSAIDs) and the relevant mechanismsExpand
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Comparison of efficacies between stents for malignant colorectal obstruction: a randomized, prospective study.
BACKGROUND Colonoscopic insertion of a self-expandable metallic stent (SEMS) has been widely performed for the treatment of malignant colorectal obstruction. Different types of stents could influenceExpand
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Bovine colostrum inhibits nuclear factor kappaB-mediated proinflammatory cytokine expression in intestinal epithelial cells.
Colostrum, a nutrient-rich fluid produced by female mammals immediately after giving birth, is loaded with several immune, growth, and tissue repair factors. However, it remains unknown whetherExpand
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Effects of Hyosine N-butyl bromide on the detection of polyps during colonoscopy.
BACKGROUND/AIMS Colonoscopy has a significant miss rate for colorectal polyp screening. The present study hypothesized that reduced colonic spasm with antispasmodic agents might yield a better visualExpand
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Risk Factors for Treatment Failure and Recurrence after Metronidazole Treatment for Clostridium difficile-associated Diarrhea.
BACKGROUND/AIMS The incidence of treatment failure or recurrence of Clostridium difficile-associated diarrhea (CDAD) following metronidazole treatment has increased recently. We studied the treatmentExpand
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Advanced Synchronous Adenoma but Not Simple Adenoma Predicts the Future Development of Metachronous Neoplasia in Patients With Resected Colorectal Cancer
Background Patients with resected colorectal cancer remain at a high risk for developing metachronous neoplasia in the remnant colorectum. The aim of this study was to identify baseline clinical andExpand
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Treatment outcome of transcatheter arterial chemoinfusion according to anticancer agents and prognostic factors in patients with advanced hepatocellular carcinoma (TNM stage IVa).
Transcatheter arterial chemoinfusion (TACI) is the main treatment modality for advanced hepatocellular carcinoma (HCC). However, the therapeutic efficacy of TACI according to anti-cancer agents andExpand
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Negative capsule endoscopy without subsequent enteroscopy does not predict lower long-term rebleeding rates in patients with obscure GI bleeding.
BACKGROUND Capsule endoscopy (CE) is now widely accepted as a first-line diagnostic modality for obscure GI bleeding (OGIB). However, the clinical implications of negative results of CE studiesExpand
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