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ORC5 gene

Known as: origin recognition complex subunit 5, PPP1R117, protein phosphatase 1, regulatory subunit 117 
This gene plays a role in DNA binding and the initiation of DNA replication. It is also involved in negative regulation of transcription.
National Institutes of Health

Related topics

Related topics

5 relations
Cell Viability ProcessDNA ReplicationORC5L protein, humanReplication Initiation

Papers overview

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2012
2012
Identification of E2F target genes that are rate limiting for dE2F1‐dependent cell proliferation
Background: Microarray studies have shown that the E2F transcription factor influences the expression of many genes but it is… 
2009
2009
Linkage between Phosphorylation of the Origin Recognition Complex and Its ATP Binding Activity in Saccharomyces cerevisiae*
The initiation of chromosomal DNA replication is tightly regulated to achieve genome replication just once per cell cycle and… 
2007
2007
Analysis of origin recognition complex in saccharomyces cerevisiae by use of Degron mutants.
Origin recognition complex (ORC), a six-protein complex (Orc1p-Orc6p), may deeply involve in initiation of chromosomal DNA… 
2007
2007
Mechanism for the degradation of origin recognition complex containing Orc5p with a defective Walker A motif and its suppression by over-production of Orc4p in yeast cells.
Orc5p is one of six subunits constituting the ORC (origin recognition complex), a possible initiator of chromosomal DNA… 
2004
2004
Analysis on Origin Recognition Complex containing Orc5p with defective Walker A Motif*
Orc5p is one of six proteins that make up the origin recognition complex (ORC), a candidate initiator of chromosomal DNA… 
Highly Cited
2003
Highly Cited
2003
mRNAs Encoding Telomerase Components and Regulators Are Controlled by UPF Genes in Saccharomyces cerevisiae
ABSTRACT Telomeres, the chromosome ends, are maintained by a balance of activities that erode and replace the terminal DNA… 
2003
2003
Kinetics of ATP Binding to the Origin Recognition Complex of Saccharomyces cerevisiae*
Origin recognition complex (ORC), a candidate initiator of chromosomal DNA replication in eukaryotes, binds specifically to ATP… 
2002
2002
Separable Functions of ORC5 in Replication Initiation and Silencing in Saccharomyces c e r e a e
Origin recognition complex (ORC) is a six subunit complex that functions as the replication initiator and is required for… 
2001
2001
Mutation analysis of the origin recognition complex subunit 5 (ORC5L) gene in adult patients with myeloid leukemias exhibiting deletions of chromosome band 7q22
Abstract. The ORC5L gene encoding a subunit of the human origin recognition complex (ORC) maps to chromosome band 7q22, a region… 
2000
2000
Kluyveromyces lactis Sir2p regulates cation sensitivity and maintains a specialized chromatin structure at the cryptic alpha-locus.
In Saccharomyces cerevisiae, transcriptional silencing of the cryptic mating type loci requires the formation of a… 
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