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ORC2L protein, human

Known as: Origin Recognition Complex Subunit 2-Like, Origin Recognition Complex Subunit 2, origin recognition complex, subunit 2, human 
Origin recognition complex subunit 2 (577 aa, ~66 kDa) is encoded by the human ORC2 gene. This protein is involved in DNA replication initiation.
National Institutes of Health

Related topics

Related topics

13 relations
Cell CycleCell Cycle ControlCell Viability ProcessDNA-Binding Proteins

Broader (2)

Origin Recognition Complex, Subunit 2origin recognition complex

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Structural insight into the unique dsDNA binding topology of the human ORC2 wing helix domain
The origin recognition complex (ORC) is indispensable for the initiation of DNA replication during the cell cycle. The DNA… 
Review
2015
Review
2015
ResearchGlobal expression studies in baker ' s yeast reveal target genes for the improvement of industrially-relevant traits : the cases of CAF 16 and ORC 2
Background: Recent years have seen a huge growth in the market of industrial yeasts with the need for strains affording better… 
Review
2015
Review
2015
Mitochondrial transporters for ornithine and related amino acids: a review
Among the members of the mitochondrial carrier family, there are transporters that catalyze the translocation of ornithine and… 
2014
2014
Protein phosphatase 1 dephosphorylates Orc2.
2012
2012
Orc2 protects ORCA from ubiquitin-mediated degradation
Origin recognition complex (ORC) is highly dynamic, with several ORC subunits getting posttranslationally modified by… 
2012
2012
Kein Karzinomrisiko unter Insulin Glargin
  • D. Einecke
  • MMW - Fortschritte der Medizin
  • 2012
  • Corpus ID: 68921453
Die Hoffnungen, bei Typ-2-Diabetes mit einer ungewöhnlich frühen Basalinsulin-Behandlung nebst normnaher Blutglukoseeinstellung… 
2008
2008
Biochemical characterization of the minichromosome maintenance (MCM) protein of the crenarchaeote Aeropyrum pernix and its interactions with the origin recognition complex (ORC) proteins.
Replication in archaea is carried out by proteins that are homologues of eukaryotic counterparts. However, the archaeal systems… 
2005
2005
Novel Splicing Variant of Mouse Orc1 Is Deficient in Nuclear Translocation and Resistant for Proteasome-mediated Degradation*
DNA replication is controlled by the stepwise assembly of the pre-replicative complex and the replication apparatus. Loading of… 
Highly Cited
2004
Highly Cited
2004
Conformational changes induced by nucleotide binding in Cdc6/ORC from Aeropyrum pernix.
1996
1996
Mouse and human homologues of the yeast origin of replication recognition complex subunit ORC2 and chromosomal localization of the cognate human gene ORC2L.
ORC2 is a subunit of the origin recognition complex in yeast and has been implicated in the initiation of DNA replication and… 
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