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ORC2L protein, human

Known as: Origin Recognition Complex Subunit 2-Like, Origin Recognition Complex Subunit 2, origin recognition complex, subunit 2, human 
Origin recognition complex subunit 2 (577 aa, ~66 kDa) is encoded by the human ORC2 gene. This protein is involved in DNA replication initiation.
National Institutes of Health

Papers overview

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2012
2012
Background: Origin recognition complex (ORC) binds to the replication origin for initiation of eukaryotic chromosome replication… Expand
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2012
2012
Origin recognition complex (ORC) is highly dynamic, with several ORC subunits getting posttranslationally modified by… Expand
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Highly Cited
2007
Highly Cited
2007
High-fidelity chromosomal segregation requires the properly timed establishment of sister-chromatid cohesion mediated by the… Expand
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2006
2006
The Origin Recognition Complex (ORC) is a critical component of replication initiation. We have previously reported generation of… Expand
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Highly Cited
2005
Highly Cited
2005
The origin recognition complex (ORC) is involved in formation of prereplicative complexes (pre-RCs) on replication origins in the… Expand
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Highly Cited
2004
Highly Cited
2004
The initiation of DNA replication in S phase requires the prior assembly of an origin recognition complex (ORC)-dependent pre… Expand
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Highly Cited
2004
Highly Cited
2004
Archaea contain one or more proteins with homology to eukaryotic ORC/Cdc6 proteins. Sequence analysis suggests the existence of… Expand
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Highly Cited
2003
Highly Cited
2003
Two isoforms of the human ornithine carrier, ORC1 and ORC2, have been identified by overexpression of the proteins in bacteria… Expand
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Highly Cited
2001
Highly Cited
2001
A hypomorphic mutation made in the ORC2 gene of a human cancer cell line through homologous recombination decreased Orc2 protein… Expand
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Highly Cited
2001
Highly Cited
2001
All the human homologs of the six subunits ofSaccharomyces cerevisiae origin recognition complex have been reported so far… Expand
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