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OPRM1 wt Allele

Known as: MOR, OPRM, Opioid Receptor, Mu-1 Gene 
Human OPRM1 wild-type allele is located within 6q24-q25 and is approximately 236 kb in length. This allele, which encodes Mu-type opioid receptor… 
National Institutes of Health

Related topics

Related topics

6 relations
6q24-q25G Protein-Coupled Receptor SignalingLigand BindingReceptor Signaling

Papers overview

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Highly Cited
2014
Highly Cited
2014
Mutation-Driven β-Lactam Resistance Mechanisms among Contemporary Ceftazidime-Nonsusceptible Pseudomonas aeruginosa Isolates from U.S. Hospitals
ABSTRACT OprD loss and hyperexpression of AmpC, MexAB-OprM, MexCD-OprJ, MexEF-OprN, and MexXY-OprM were evaluated among 120… 
Highly Cited
2011
Highly Cited
2011
Role of the MexEF-OprN Efflux System in Low-Level Resistance of Pseudomonas aeruginosa to Ciprofloxacin
ABSTRACT In this study, we investigated the resistance mechanisms to fluoroquinolones of 85 non-cystic fibrosis strains of… 
Highly Cited
2007
Highly Cited
2007
Resistance Mechanisms of Multiresistant Pseudomonas aeruginosa Strains from Germany and Correlation with Hypermutation
ABSTRACT In this study, we analyzed the mechanisms of multiresistance for 22 clinical multiresistant and clonally different… 
Highly Cited
2005
Highly Cited
2005
Molecular Basis of Azithromycin-Resistant Pseudomonas aeruginosa Biofilms
ABSTRACT Pseudomonas aeruginosa biofilms are extremely recalcitrant to antibiotic treatment. Treatment of cystic fibrosis… 
Highly Cited
2001
Highly Cited
2001
Pseudomonas aeruginosa Reveals High Intrinsic Resistance to Penem Antibiotics: Penem Resistance Mechanisms and Their Interplay
ABSTRACT Pseudomonas aeruginosa exhibits high intrinsic resistance to penem antibiotics such as faropenem, ritipenem, AMA3176… 
Highly Cited
2000
Highly Cited
2000
Contribution of the MexX-MexY-OprM Efflux System to Intrinsic Resistance in Pseudomonas aeruginosa
ABSTRACT To test the possibility that MexX-MexY, a new set of efflux system components, is associated with OprM and contributes… 
Highly Cited
1999
Highly Cited
1999
Spinal antinociceptive synergism between morphine and clonidine persists in mice made acutely or chronically tolerant to morphine.
Morphine (Mor) tolerance has been attributed to a reduction of opioid-adrenergic antinociceptive synergy at the spinal level. The… 
Highly Cited
1998
Highly Cited
1998
Expression of Pseudomonas aeruginosa Multidrug Efflux Pumps MexA-MexB-OprM and MexC-MexD-OprJ in a Multidrug-Sensitive Escherichia coli Strain
ABSTRACT The mexCD-oprJ and mexAB-oprM operons encode components of two distinct multidrug efflux pumps inPseudomonas aeruginosa… 
Highly Cited
1998
Highly Cited
1998
Contribution of Outer Membrane Efflux Protein OprM to Antibiotic Resistance in Pseudomonas aeruginosa Independent of MexAB
ABSTRACT A Pseudomonas aeruginosa strain carrying an insertion of an ΩHg interposon in the mexB gene (mexB::ΩHg; strain K879… 
Highly Cited
1992
Highly Cited
1992
Cross-resistance to meropenem, cephems, and quinolones in Pseudomonas aeruginosa
Multiple-drug-resistant mutants were isolated from Pseudomonas aeruginosa PAO1 on agar plates containing ofloxacin and cefsulodin… 
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