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OPC 21268

Known as: Acetamide, N-(3-(4-((4-(3,4-dihydro-2-oxo-1(2H)-quinolinyl)-1-piperidinyl)carbonyl)phenoxy)propyl)-, OPC-21268 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

PiperidinesQuinolonesVasopressin Antagonist

Papers overview

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2008
2008
Effects of arginine vasotocin and vasopressin receptor antagonists on Na+ and Cl- transport in the isolated skin of two frog species, Hyla japonica and Rana nigromaculata.
2004
2004
Regional differences in the expression of Fos-like immunoreactivity after central salt loading in conscious rats: modulation by endogenous vasopressin and role of the area postrema
1999
1999
Characterization of rodent liver and kidney AVP receptors: pharmacologic evidence for species differences
1999
1999
Participation of arterial baroreceptors input and peripheral vasopressin in the suppression of renal sympathetic nerve activity induced by central salt loading in conscious rats.
1996
1996
Effect of a nonpeptide vasopressin V1 antagonist (OPC-21268) on experimental accelerated focal glomerulosclerosis.
The effects of the nonpeptide orally effective vasopressin V1 receptor antagonist OPC-21268 were studied in progressive focal… 
1994
1994
Vasopressin and a nonpeptide antidiuretic hormone receptor antagonist (OPC-31260).
The development of nonpeptide orally active AVP analogues has provided a new tool with which to assess the physiological and… 
1993
1993
Characterization of a novel non-peptide vasopressin V1 receptor antagonist (OPC-21268) in the rat.
A non-peptide, orally effective, vasopressin (AVP) V1 receptor antagonist 1-(1-[4-(3-acetylaminopropoxy) benzoyl]-4-piperidyl)-3… 
1993
1993
Distinct mechanisms of action of V1 antagonists OPC-21268 and [d(CH2)5Tyr(Me)AVP] in mesangial cells.
The effects of two arginine vasopressin (AVP) V1 receptor antagonists, a peptide analogue [d(CH2)5Tyr(Me)AVP] and an orally… 
1992
1992
Effects of a Nonpeptide Vasopressin Antagonist (OPC‐21268) on Cytosolic Ca2+ Concentration in Vascular and Cardiac Myocytes
A selective V, antagonist, l-{l-[4(3-acetylaminopropoxy)benzoyl]-4-piperidyl}-3,4-dihydro-2(1H)-quinolinone (OPC-21268), which is… 
1992
1992
Blocking effects of OPC-21268 and OPC-31260 (vasopressin V1- and V2-receptor antagonists) on vasopressin-induced constrictions in isolated, perfused dog femoral arteries.
Using a perfusion technique of isolated vessels, constrictor responses to vasopressin (VP) and norepinephrine (NE) were… 
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