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Nucleosomes

Known as: DNA protein particle, Nucleosome, Nucleosomes [Chemical/Ingredient] 
A DNA packaging complex comprised of approximately 200 base pairs of DNA wound around a protein core, which is formed by an octomer of histones. The… 
National Institutes of Health

Related topics

Related topics

38 relations

Broader (4)

Cell NucleusCell Nucleus StructuresChromatinChromosomes
Core Histone Macro-H2ACore Histone Macro-H2A.1, humanH2AX protein, humanHMGN Proteins

Narrower (3)

DinucleosomesPolynucleosomesnucleosome assembly

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
A 1,2-d(GpG) cisplatin intrastrand cross-link influences the rotational and translational setting of DNA in nucleosomes.
The mechanism of action of platinum-based anticancer drugs such as cis-diamminedichloroplatinum(II), or cisplatin, involves three… 
Highly Cited
1999
Highly Cited
1999
Abnormal DNA methylation and deoxycytosine‐deoxyguanine content in nucleosomes from lymphocytes undergoing apoptosis
Systemic lupus erythematosus (SLE) is characterized by an accelerated apoptosis of peripheral lymphocytes and an impairment of… 
1993
1993
UV damage to DNA strongly influences its rotational setting on the histone surface of reconstituted nucleosomes.
The major photoproduct formed in DNA, following absorption of ultraviolet (UV) light, is the cis-syn cyclobutane pyrimidine dimer… 
1988
1988
"Ultraviolet footprinting" accurately maps sequence-specific contacts and DNA kinking in the EcoRI endonuclease-DNA complex.
The "UV footprinting" technique has been used to detect contacts between EcoRI endonuclease and its recognition sequence at… 
Highly Cited
1985
Highly Cited
1985
Sequence-dependent bending of DNA and phasing of nucleosomes.
Conformational analysis has revealed anisotropic flexibility of the B-DNA double helix: it bends most easily into the grooves… 
Highly Cited
1980
Highly Cited
1980
Salt induced transitions of chromatin core particles studied by tyrosine fluorescence anisotropy.
Chromatin core particles containing 146 base pairs of DNA have been found to undergo a single defined transition below 10 mM… 
Highly Cited
1980
Highly Cited
1980
Unfolding of nucleosomes by ethidium binding.
We report spectroscopic, hydrodynamic, and biochemical studies on the complex of ethidium bromide with 140 base pair nucleosomal… 
1980
1980
Nucleosomes structure and its dynamic transitions
  • A. Mirzabekov
  • Quarterly Reviews of Biophysics (print)
  • 1980
  • Corpus ID: 5474638
The discovery of nucleosomes as a basic repeating unit of the chromatin structure organizing the major part of eukaryotic DNA… 
Highly Cited
1979
Highly Cited
1979
Chromatin fractionation procedure that yields nucleosomes containing near-stoichiometric amounts of high mobility group nonhistone chromosomal proteins.
Initial results of an approach to the isolation of functionally active chromatin are described. Slight digestion of mouse myeloma… 
Highly Cited
1979
Highly Cited
1979
Reassociation of histone H1 with nucleosomes.
The role of histone H1 in nucleosome heterogeneity and structure has been studied using a reconstitution procedure. Histone H1… 
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