Core Histone Macro-H2A

Known as: Histone MacroH2A, MacroH2A, mH2A 
A histone protein that is comprised of a histone H2A domain, which allows interaction with the nucleosome, and a macro domain, which may bind to ADP… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Cancer is a disease consisting of both genetic and epigenetic changes. Although increasing evidence demonstrates that tumour… (More)
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Highly Cited
2009
Highly Cited
2009
The histone variants macroH2A1 and macroH2A2 are associated with X chromosome inactivation in female mammals. However, the… (More)
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Highly Cited
2005
Highly Cited
2005
Histone macroH2A is a hallmark of mammalian heterochromatin. Here we show that human macroH2A1.1 binds the SirT1-metabolite O… (More)
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Highly Cited
2005
Highly Cited
2005
X inactivation involves the stable silencing of one of the two X chromosomes in XX female mammals. Initiation of this process… (More)
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Highly Cited
2003
Highly Cited
2003
The unusual histone variant macroH2A (mH2A) has been associated with repression of transcription, but the molecular mechanisms by… (More)
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Highly Cited
2001
Highly Cited
2001
Chromatin on the mammalian inactive X chromosome differs in a number of ways from that on the active X. One protein, macroH2A… (More)
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Highly Cited
2001
Highly Cited
2001
MacroH2A1 is an unusual variant of the core histone H2A which is enriched in chromatin on the inactive X chromosome of female… (More)
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Highly Cited
2001
Highly Cited
2001
MACROH2As are core histones that have a unique hybrid structure consisting of an amino-terminal domain that closely resembles a… (More)
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Highly Cited
1998
Highly Cited
1998
In female mammals one of the X chromosomes is rendered almost completely transcriptionally inactive, to equalize expression of X… (More)
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Highly Cited
1992
Highly Cited
1992
A histone, macroH2A, nearly three times the size of conventional H2A histone, was found in rat liver nucleosomes. Its N-terminal… (More)
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