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A role for bone morphogenetic proteins in the induction of cardiac myogenesis.
TLDR
It is demonstrated that bone morphogenetic protein (BMP) signaling plays a central role in the induction of cardiac myogenesis in the chick embryo and implies that a cardiogenic field exists in the anterior mesoderm and that localized expression of BMPs selects which cells within this field enter the cardiac myocyte lineage.
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Epicardial retinoid X receptor alpha is required for myocardial growth and coronary artery formation.
TLDR
It is shown that RXRalpha signaling in the epicardium is required for proper cardiac morphogenesis and a retinoid-dependent Wnt signaling pathway that cooperates in epicardial epithelial-to-mesenchymal transformation is identified.
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The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature
TLDR
The studies show that the gut is initially devoid of a mesothelium but that serosal mesothelial cells expressing the Wilm's tumor protein (Wt1) move to and over the gut, and reveal a conserved mechanism in blood vessel formation to coelomic organs.
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Epicardial retinoid X receptor is required for myocardial growth and coronary artery formation
TLDR
It is shown that RXR α signaling in the epicardium is required for proper cardiac morphogenesis and an additional phenotype of defective coronary arteriogenesis associated with RXRα deficiency is detected and a retinoid-dependent Wnt signaling pathway that cooperates in epicardial epithelial-to-mesenchymal transformation is identified.
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Reach‐ and catchment‐scale determinants of the distribution of freshwater mussels (Bivalvia: Unionidae) in south‐eastern Michigan, U.S.A.
SUMMARY 1. We investigated the diversity and distribution of freshwater mussels at 40 sites in an agricultural catchment, the River Raisin in south-eastern Michigan, to relate mussel assemblages and…
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Freshwater unionacean clams (Mollusca, Pelecypoda) of North America
Freshwater sphaeriacean clams (Mollusca, Pelecypoda) of North America
Epicardially derived fibroblasts preferentially contribute to the parietal leaflets of the atrioventricular valves in the murine heart.
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A GATA-6 gene heart-region-specific enhancer provides a novel means to mark and probe a discrete component of the mouse cardiac conduction system
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Epicardial induction of fetal cardiomyocyte proliferation via a retinoic acid-inducible trophic factor.
TLDR
The fetal epicardium secretes trophic factors which drive fetal cardiomyocyte proliferation and promote ventricular chamber morphogenesis, in response to retinoic acid and in a manner requiring the activity of RXRalpha.
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