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A role for bone morphogenetic proteins in the induction of cardiac myogenesis.
- T. Schultheiss, J. Burch, A. Lassar
- Biology, Medicine
- Genes & development
- 15 February 1997
Little is known about the molecular mechanisms that govern heart specification in vertebrates. Here we demonstrate that bone morphogenetic protein (BMP) signaling plays a central role in the… Expand
GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut.
- A. Laverriere, C. Macneill, C. Müller, R. Poelmann, J. Burch, T. Evans
- Biology, Medicine
- The Journal of biological chemistry
- 16 September 1994
We describe experiments which show that: 1) two previously identified members of the GATA family of transcription factors (both of which were originally called GATA-4) correspond to chicken cDNAs for… Expand
Epicardial retinoid X receptor alpha is required for myocardial growth and coronary artery formation.
- E. Merki, M. Zamora, +9 authors P. Ruiz-Lozano
- Medicine
- Proceedings of the National Academy of Sciences…
- 2005
Vitamin A signals play critical roles during embryonic development. In particular, heart morphogenesis depends on vitamin A signals mediated by the retinoid X receptor alpha (RXRalpha), as the… Expand
Reach‐ and catchment‐scale determinants of the distribution of freshwater mussels (Bivalvia: Unionidae) in south‐eastern Michigan, U.S.A.
SUMMARY 1. We investigated the diversity and distribution of freshwater mussels at 40 sites in an agricultural catchment, the River Raisin in south-eastern Michigan, to relate mussel assemblages and… Expand
Epicardial retinoid X receptor is required for myocardial growth and coronary artery formation
- E. Merki, M. Zamora, +9 authors P. Ruiz-Lozano
- Biology
- 20 December 2005
Vitamin A signals play critical roles during embryonic development. In particular, heart morphogenesis depends on vitamin A signals mediated by the retinoid X receptor α (RXRα), as the systemic… Expand
The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature
- B. Wilm, Annemieke Ipenberg, N. Hastie, J. Burch, D. Bader
- Biology, Medicine
- Development
- 1 December 2005
Most internal organs are situated in a coelomic cavity and are covered by a mesothelium. During heart development, epicardial cells (a mesothelium) move to and over the heart, undergo… Expand
Epicardial induction of fetal cardiomyocyte proliferation via a retinoic acid-inducible trophic factor.
Mouse embryos lacking the retinoic acid receptor RXRalpha properly undergo the early steps of heart development, but then fail to initiate a proliferative expansion of cardiomyocytes that normally… Expand
A GATA-6 gene heart-region-specific enhancer provides a novel means to mark and probe a discrete component of the mouse cardiac conduction system
- D. L. Davis, A. Edwards, A. Juraszek, A. Phelps, A. Wessels, J. Burch
- Biology, Medicine
- Mechanisms of Development
- 1 October 2001
The transcriptional programs that specify the distinct components of the cardiac conduction system are poorly understood, in part due to a paucity of definitive molecular markers. In the present… Expand
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