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Nucleoside-Diphosphate Kinase

Known as: Kinases, Nucleoside-Diphosphate, Diphosphate Kinases, Deoxynucleoside, Deoxynucleoside Diphosphate Kinases 
An enzyme that is found in mitochondria and in the soluble cytoplasm of cells. It catalyzes reversible reactions of a nucleoside triphosphate, e.g… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
BACKGROUND Niraparib is an oral poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) 1/2 inhibitor that has shown clinical… Expand
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Prostate cancer is a heterogeneous disease, but current treatments are not based on molecular stratification. We… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Olaparib (AZD2281) is an oral poly(adenosine diphosphate [ADP]-ribose) polymerase inhibitor that has shown antitumor… Expand
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Highly Cited
2011
Highly Cited
2011
A genome stability regulator integrates DNA repair and stress signaling pathways. Sirtuin 6 (SIRT6) is a mammalian homolog of the… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The inhibition of poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) is a potential synthetic lethal… Expand
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Highly Cited
2006
Highly Cited
2006
Multiple enzymatic activities are required for transcriptional initiation. The enzyme DNA topoisomerase II associates with gene… Expand
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Review
2000
Review
2000
Biochemical experiments over the past 40 years have shown that nucleoside diphosphate(NDP) kinase activity, which catalyzes… Expand
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Highly Cited
2000
Highly Cited
2000
Isopentenyl diphosphate (IPP) is the central intermediate in the biosynthesis of isoprenoids, the most ancient and diverse class… Expand
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Highly Cited
1998
Highly Cited
1998
Tankyrase, a protein with homology to ankyrins and to the catalytic domain of poly(adenosine diphosphate-ribose) polymerase (PARP… Expand
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Review
1985
Review
1985
There is convincing evidence that cellular prooxidant states--that is, increased concentrations of active oxygen and organic… Expand
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