Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Nucleoside-Diphosphate Kinase

Known as: Kinases, Nucleoside-Diphosphate, Diphosphate Kinases, Deoxynucleoside, Deoxynucleoside Diphosphate Kinases 
An enzyme that is found in mitochondria and in the soluble cytoplasm of cells. It catalyzes reversible reactions of a nucleoside triphosphate, e.g… Expand
National Institutes of Health

Related topics

Related topics

15 relations
CMPK2 geneIn BloodProcess of secretionantagonists & inhibitors
Expand

Narrower (5)

NBR-A isoenzymeNBR-B isoenzymeNDPK-B protein, humannucleoside diphosphate kinase 2
Expand

Broader (1)

Phosphotransferases, ATP

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Niraparib Maintenance Therapy in Platinum-Sensitive, Recurrent Ovarian Cancer.
BACKGROUND Niraparib is an oral poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) 1/2 inhibitor that has shown clinical… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Highly Cited
2015
Highly Cited
2015
DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer.
BACKGROUND Prostate cancer is a heterogeneous disease, but current treatments are not based on molecular stratification. We… Expand
  • table 1
  • table 2
  • figure 2
Highly Cited
2012
Highly Cited
2012
Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer.
BACKGROUND Olaparib (AZD2281) is an oral poly(adenosine diphosphate [ADP]-ribose) polymerase inhibitor that has shown antitumor… Expand
  • figure 1
  • table 1
  • table 1
  • figure 2
  • table 2
Highly Cited
2009
Highly Cited
2009
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers.
BACKGROUND The inhibition of poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) is a potential synthetic lethal… Expand
  • table 1
  • table 2
  • table 3
Review
2000
Review
2000
The Human Nm23/Nucleoside Diphosphate Kinases
Biochemical experiments over the past 40 years have shown that nucleoside diphosphate(NDP) kinase activity, which catalyzes… Expand
Highly Cited
2000
Highly Cited
2000
Isoprenoid biosynthesis: the evolution of two ancient and distinct pathways across genomes.
Isopentenyl diphosphate (IPP) is the central intermediate in the biosynthesis of isoprenoids, the most ancient and diverse class… Expand
  • figure 1
  • figure 2
Highly Cited
1998
Highly Cited
1998
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres.
Tankyrase, a protein with homology to ankyrins and to the catalytic domain of poly(adenosine diphosphate-ribose) polymerase (PARP… Expand
Highly Cited
1993
Highly Cited
1993
Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis.
A human gene encoding the c-myc purine-binding transcription factor PuF was identified by screening of a cervical carcinoma cell… Expand
Review
1985
Review
1985
Prooxidant states and tumor promotion.
There is convincing evidence that cellular prooxidant states--that is, increased concentrations of active oxygen and organic… Expand
Highly Cited
1985
Highly Cited
1985
Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment
Vertebrate rod photoreceptors hyperpolarize when illuminated, due to the closing of cation-selective channels in the plasma… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE