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- Publications
- Influence
A novel virus in swine is closely related to the human hepatitis E virus.
- X. J. Meng, R. Purcell, +6 authors S. Emerson
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 2 September 1997
A novel virus, designated swine hepatitis E virus (swine HEV), was identified in pigs. Swine HEV crossreacts with antibody to the human HEV capsid antigen. Swine HEV is a ubiquitous agent and the… Expand
Hepatitis E virus
- S. Emerson, R. Purcell
- Biology, Medicine
- Reviews in medical virology
- 1 May 2003
Hepatitis E virus (HEV) is a positive‐stranded RNA virus with a 7.2 kb genome that is capped and polyadenylated. The virus is currently unclassified: the organisation of the genome resembles that of… Expand
A virus discovery method incorporating DNase treatment and its application to the identification of two bovine parvovirus species
- T. Allander, S. Emerson, R. Engle, R. Purcell, J. Bukh
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 18 September 2001
Identification of previously unrecognized viral agents in serum or plasma samples is of great medical interest but remains a major challenge, primarily because of abundant host DNA. The current… Expand
Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee.
- M. Yanagi, R. Purcell, S. Emerson, J. Bukh
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 5 August 1997
We have succeeded in constructing a stable full-length cDNA clone of strain H77 (genotype 1a) of hepatitis C virus (HCV). We devised a cassette vector with fixed 5' and 3' termini and constructed… Expand
Prevalence of Antibodies to Hepatitis E Virus in Veterinarians Working with Swine and in Normal Blood Donors in the United States and Other Countries
- X. Meng, B. Wiseman, +5 authors R. Purcell
- Medicine
- Journal of Clinical Microbiology
- 1 January 2002
ABSTRACT Hepatitis E virus (HEV) is endemic in many developing and some industrialized countries. It has been hypothesized that animals may be the source of infection. The recent identification of… Expand
Hepatitis E: an emerging awareness of an old disease.
- R. Purcell, S. Emerson
- Medicine
- Journal of hepatology
- 1 March 2008
Although hepatitis E was recognized as a new disease in 1980, the virus was first visualized in 1983 and its genome was cloned and characterized in 1991, the disease is probably ancient but not… Expand
A Bicistronic Subgenomic mRNA Encodes both the ORF2 and ORF3 Proteins of Hepatitis E Virus
- J. Graff, U. Torian, H. Nguyen, S. Emerson
- Biology, Medicine
- Journal of Virology
- 15 June 2006
ABSTRACT Hepatitis E virus replicons containing the neomycin resistance gene expressed from open reading frames (ORFs) 2 and 3 were transfected into Huh-7 cells, and stable cell lines containing… Expand
Consensus proposals for classification of the family Hepeviridae
- D. B. Smith, P. Simmonds, +6 authors M. Purdy
- Biology, Medicine
- The Journal of general virology
- 2 July 2014
The family Hepeviridae consists of positive-stranded RNA viruses that infect a wide range of mammalian species, as well as chickens and trout. A subset of these viruses infects humans and can cause a… Expand
Genetic and Experimental Evidence for Cross-Species Infection by Swine Hepatitis E Virus
- X. J. Meng, P. Halbur, +5 authors S. Emerson
- Biology, Medicine
- Journal of Virology
- 1 December 1998
ABSTRACT Prior to the recent discovery of the swine hepatitis E virus (swine HEV) in pigs from the midwestern United States, HEV was not considered endemic to this country. Since swine HEV is… Expand
Characterization of a prototype strain of hepatitis E virus.
- S. A. Tsarev, S. Emerson, +5 authors R. Purcell
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 15 January 1992
A strain of hepatitis E virus (SAR-55) implicated in an epidemic of enterically transmitted non-A, non-B hepatitis, now called hepatitis E, was characterized extensively. Six cynomolgus monkeys… Expand
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